Annual report

Period2022-01-01 → 2022-12-31

Filed2023-03-29

StandardIFRS

ConsolidatedYes

Data checks20 of 20 passed

Key figures · 136

Metric	Value	Period	Scope	Source row
Revenue	¥90m	2022-01-01 → 2022-12-31	Cons.	Revenue IFRS
Revenue	¥41m	2021-01-01 → 2021-12-31	Cons.	Revenue IFRS
Revenue	¥27m	2020-01-01 → 2020-12-31^d	Cons.	Revenue IFRS (5-year summary)
Revenue	¥89m	2019-01-01 → 2019-12-31^d	Cons.	Revenue IFRS (5-year summary)
Operating income	−¥5.2bn	2022-01-01 → 2022-12-31	Cons.	Operating profit loss IFRS
Operating income	−¥5.4bn	2021-01-01 → 2021-12-31	Cons.	Operating profit loss IFRS
Profit before tax	−¥5.3bn	2022-01-01 → 2022-12-31	Cons.	Profit loss before tax IFRS
Profit before tax	−¥4.5bn	2021-01-01 → 2021-12-31	Cons.	Profit loss before tax IFRS
Profit before tax	−¥5.4bn	2020-01-01 → 2020-12-31^d	Cons.	Profit loss before tax IFRS (5-year summary)
Profit before tax	−¥4.6bn	2019-01-01 → 2019-12-31^d	Cons.	Profit loss before tax IFRS (5-year summary)
Net income (owners)	−¥5.2bn	2022-01-01 → 2022-12-31	Cons.	Profit loss attributable to owners of parent IFRS
Net income (owners)	−¥4.9bn	2021-01-01 → 2021-12-31	Cons.	Profit loss attributable to owners of parent IFRS
Net income (owners)	−¥5.5bn	2020-01-01 → 2020-12-31^d	Cons.	Profit loss attributable to owners of parent IFRS (5-year summary)
Net income (owners)	−¥4.8bn	2019-01-01 → 2019-12-31^d	Cons.	Profit loss attributable to owners of parent IFRS (5-year summary)
Net income	−¥5.2bn	2022-01-01 → 2022-12-31	Cons.	Profit loss IFRS
Net income	−¥4.9bn	2021-01-01 → 2021-12-31	Cons.	Profit loss IFRS
Total assets	¥15.0bn	at 2022-12-31	Cons.	Assets IFRS
Total assets	¥24.0bn	at 2021-12-31	Cons.	Assets IFRS
Total assets	¥23.2bn	at 2020-12-31^d	Cons.	Total assets IFRS (5-year summary)
Total assets	¥25.6bn	at 2019-12-31^d	Cons.	Total assets IFRS (5-year summary)
Total assets	¥19.6bn	at 2018-12-31^d	Cons.	Total assets IFRS (5-year summary)
Total liabilities	¥10.7bn	at 2022-12-31	Cons.	Liabilities IFRS
Total liabilities	¥15.3bn	at 2021-12-31	Cons.	Liabilities IFRS
Net assets / equity	¥4.4bn	at 2022-12-31	Cons.	Equity IFRS
Net assets / equity	¥8.6bn	at 2021-12-31	Cons.	Equity IFRS
Net assets / equity	¥7.9bn	at 2020-12-31^d	Cons.	Equity IFRS
Equity (owners)	¥4.4bn	at 2022-12-31	Cons.	Equity attributable to owners of parent IFRS
Equity (owners)	¥8.6bn	at 2021-12-31	Cons.	Equity attributable to owners of parent IFRS
Equity (owners)	¥7.8bn	at 2020-12-31^d	Cons.	Equity attributable to owners of parent IFRS (5-year summary)
Equity (owners)	¥12.3bn	at 2019-12-31^d	Cons.	Equity attributable to owners of parent IFRS (5-year summary)
Equity (owners)	¥14.4bn	at 2018-12-31^d	Cons.	Equity attributable to owners of parent IFRS (5-year summary)
Cash & equivalents	¥7.2bn	at 2022-12-31	Cons.	Cash and cash equivalents IFRS
Cash & equivalents	¥15.1bn	at 2021-12-31	Cons.	Cash and cash equivalents IFRS
Cash & equivalents	¥13.9bn	at 2020-12-31^d	Cons.	Cash and cash equivalents IFRS
Cash & equivalents	¥18.3bn	at 2019-12-31^d	Cons.	Cash and cash equivalents IFRS (5-year summary)
Operating cash flow	−¥4.6bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in operating activities IFRS
Operating cash flow	−¥5.1bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in operating activities IFRS
Operating cash flow	−¥3.9bn	2020-01-01 → 2020-12-31^d	Cons.	Cash flows from used in operating activities IFRS (5-year summary)
Operating cash flow	−¥4.9bn	2019-01-01 → 2019-12-31^d	Cons.	Cash flows from used in operating activities IFRS (5-year summary)
Investing cash flow	−¥909m	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in investing activities IFRS
Investing cash flow	−¥736m	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in investing activities IFRS
Investing cash flow	−¥1.2bn	2020-01-01 → 2020-12-31^d	Cons.	Cash flows from used in investing activities IFRS (5-year summary)
Investing cash flow	−¥32m	2019-01-01 → 2019-12-31^d	Cons.	Cash flows from used in investing activities IFRS (5-year summary)
Financing cash flow	−¥2.5bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in financing activities IFRS
Financing cash flow	¥7.0bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in financing activities IFRS
Financing cash flow	¥803m	2020-01-01 → 2020-12-31^d	Cons.	Cash flows from used in financing activities IFRS (5-year summary)
Financing cash flow	¥11.4bn	2019-01-01 → 2019-12-31^d	Cons.	Cash flows from used in financing activities IFRS (5-year summary)
EPS (basic)	¥-90.67	2022-01-01 → 2022-12-31	Cons.	Basic earnings loss per share IFRS
EPS (basic)	¥-93.36	2021-01-01 → 2021-12-31	Cons.	Basic earnings loss per share IFRS
EPS (basic)	¥-107.2	2020-01-01 → 2020-12-31^d	Cons.	Basic earnings loss per share IFRS (5-year summary)
EPS (basic)	¥-95.86	2019-01-01 → 2019-12-31^d	Cons.	Basic earnings loss per share IFRS (5-year summary)
EPS (diluted)	¥-90.67	2022-01-01 → 2022-12-31	Cons.	Diluted earnings loss per share IFRS
EPS (diluted)	¥-99.51	2021-01-01 → 2021-12-31	Cons.	Diluted earnings loss per share IFRS
EPS (diluted)	¥-107.2	2020-01-01 → 2020-12-31^d	Cons.	Diluted earnings loss per share IFRS (5-year summary)
EPS (diluted)	¥-95.86	2019-01-01 → 2019-12-31^d	Cons.	Diluted earnings loss per share IFRS (5-year summary)
Net assets per share	¥69.33	at 2022-12-31	Cons.	Equity to asset ratio IFRS (5-year summary)
Net assets per share	¥156.65	at 2021-12-31	Cons.	Equity to asset ratio IFRS (5-year summary)
Net assets per share	¥151.82	at 2020-12-31^d	Cons.	Equity to asset ratio IFRS (5-year summary)
Net assets per share	¥240.6	at 2019-12-31^d	Cons.	Equity to asset ratio IFRS (5-year summary)
Net assets per share	¥291.7	at 2018-12-31^d	Cons.	Equity to asset ratio IFRS (5-year summary)
Equity ratio	29.2%	at 2022-12-31	Cons.	Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio	36.0%	at 2021-12-31	Cons.	Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio	33.9%	at 2020-12-31^d	Cons.	Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio	48.2%	at 2019-12-31^d	Cons.	Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio	73.3%	at 2018-12-31^d	Cons.	Ratio of owners equity to gross assets IFRS (5-year summary)
ROE	-79.4%	2022-01-01 → 2022-12-31	Cons.	Rate of return on equity IFRS (5-year summary)
ROE	-59.6%	2021-01-01 → 2021-12-31	Cons.	Rate of return on equity IFRS (5-year summary)
ROE	-54.6%	2020-01-01 → 2020-12-31^d	Cons.	Rate of return on equity IFRS (5-year summary)
ROE	-36.0%	2019-01-01 → 2019-12-31^d	Cons.	Rate of return on equity IFRS (5-year summary)
Employees	71	at 2022-12-31	Cons.	Number of employees
Employees	116	at 2021-12-31	Cons.	Number of employees
Employees	114	at 2020-12-31^d	Cons.	Number of employees
Employees	109	at 2019-12-31^d	Cons.	Number of employees
Employees	93	at 2018-12-31^d	Cons.	Number of employees
Revenue	¥80m	2022-01-01 → 2022-12-31	Standalone	Net sales
Operating income	−¥5.1bn	2022-01-01 → 2022-12-31	Standalone	Operating income
Operating income	−¥5.3bn	2021-01-01 → 2021-12-31	Standalone	Operating income
Ordinary income	−¥5.3bn	2022-01-01 → 2022-12-31	Standalone	Ordinary income
Ordinary income	−¥5.5bn	2021-01-01 → 2021-12-31	Standalone	Ordinary income
Ordinary income	−¥4.2bn	2020-01-01 → 2020-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥4.5bn	2019-01-01 → 2019-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥5.1bn	2018-01-01 → 2018-12-31^d	Standalone	Ordinary income loss (5-year summary)
Profit before tax	−¥8.4bn	2022-01-01 → 2022-12-31	Standalone	Income before income taxes
Profit before tax	−¥5.5bn	2021-01-01 → 2021-12-31	Standalone	Income before income taxes
Net income	−¥8.4bn	2022-01-01 → 2022-12-31	Standalone	Profit loss
Net income	−¥5.5bn	2021-01-01 → 2021-12-31	Standalone	Profit loss
Net income	−¥4.4bn	2020-01-01 → 2020-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥4.4bn	2019-01-01 → 2019-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥5.1bn	2018-01-01 → 2018-12-31^d	Standalone	Net income loss (5-year summary)
Total assets	¥9.2bn	at 2022-12-31	Standalone	Assets
Total assets	¥18.8bn	at 2021-12-31	Standalone	Assets
Total assets	¥18.4bn	at 2020-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥21.1bn	at 2019-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥15.0bn	at 2018-12-31^d	Standalone	Total assets (5-year summary)
Total liabilities	¥8.3bn	at 2022-12-31	Standalone	Liabilities
Total liabilities	¥13.0bn	at 2021-12-31	Standalone	Liabilities
Net assets / equity	¥833m	at 2022-12-31	Standalone	Net assets
Net assets / equity	¥5.8bn	at 2021-12-31	Standalone	Net assets
Net assets / equity	¥5.6bn	at 2020-12-31^d	Standalone	Net assets
Net assets / equity	¥9.0bn	at 2019-12-31^d	Standalone	Net assets (5-year summary)
Net assets / equity	¥10.8bn	at 2018-12-31^d	Standalone	Net assets (5-year summary)
Cash and deposits	¥7.0bn	at 2022-12-31	Standalone	Cash and deposits
Cash and deposits	¥14.5bn	at 2021-12-31	Standalone	Cash and deposits
Cash & equivalents	¥17.9bn	at 2019-12-31^d	Standalone	Cash and cash equivalents (5-year summary)
Cash & equivalents	¥11.6bn	at 2018-12-31^d	Standalone	Cash and cash equivalents (5-year summary)
Operating cash flow	−¥5.0bn	2019-01-01 → 2019-12-31^d	Standalone	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥5.1bn	2018-01-01 → 2018-12-31^d	Standalone	Net cash provided by used in operating activities (5-year summary)
Investing cash flow	−¥211m	2019-01-01 → 2019-12-31^d	Standalone	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥2.7bn	2018-01-01 → 2018-12-31^d	Standalone	Net cash provided by used in investing activities (5-year summary)
Financing cash flow	¥11.5bn	2019-01-01 → 2019-12-31^d	Standalone	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥392m	2018-01-01 → 2018-12-31^d	Standalone	Net cash provided by used in financing activities (5-year summary)
EPS (basic)	¥-147.59	2022-01-01 → 2022-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-104.06	2021-01-01 → 2021-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-86.24	2020-01-01 → 2020-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-87.97	2019-01-01 → 2019-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-103.53	2018-01-01 → 2018-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
Net assets per share	¥3.52	at 2022-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥98.89	at 2021-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥104.23	at 2020-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥173.01	at 2019-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥217.43	at 2018-12-31^d	Standalone	Net assets per share (5-year summary)
Equity ratio	2.4%	at 2022-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	29.0%	at 2021-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	29.3%	at 2020-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	42.0%	at 2019-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	71.5%	at 2018-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Shares issued	63,204,200	at 2022-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	55,147,900	at 2021-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	51,666,500	at 2020-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	51,270,200	at 2019-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	49,261,600	at 2018-12-31^d	Standalone	Total number of issued shares (5-year summary)
Employees	70	at 2022-12-31	Standalone	Number of employees
Employees	115	at 2021-12-31	Standalone	Number of employees
Employees	113	at 2020-12-31^d	Standalone	Number of employees
Employees	109	at 2019-12-31^d	Standalone	Number of employees
Employees	93	at 2018-12-31^d	Standalone	Number of employees

Periods use the dates stated in the filing. ^d = earlier-year period dated by calendar; ^v = that date confirmed by the company's own earlier filing.

Segments · 4

Segment	Item	Period	Value
Management Divisionreportable segment	employees	at 2022-12-31	15 pure
Research And Development Divisionreportable segment	employees	at 2022-12-31	56 pure
Management Divisionreportable segment	employees	at 2022-12-31	14 pure
Research And Development Divisionreportable segment	employees	at 2022-12-31	56 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,529

Item	Context	Value
Other information on share acquisition rights (text)	FilingDateInstant	Text · Plus
Exercises etc of moving strike convertible bonds etc (text)	FilingDateInstant	Text · Plus
Changes in number of issued shares stated capital etc (text)	FilingDateInstant	Text · Plus
Shareholding by shareholder category (text)	FilingDateInstant	Text · Plus
Major shareholders (text)	FilingDateInstant	Text · Plus
Name major shareholders	CurrentYearInstant_No1MajorShareholdersMember	Original text (Japanese) 鍵本　忠尚
Address major shareholders	CurrentYearInstant_No1MajorShareholdersMember	Original text (Japanese) 東京都港区
Name major shareholders	CurrentYearInstant_No2MajorShareholdersMember	Original text (Japanese) 株式会社ニコン
Address major shareholders	CurrentYearInstant_No2MajorShareholdersMember	Original text (Japanese) 東京都港区港南二丁目15番３号
Name major shareholders	CurrentYearInstant_No3MajorShareholdersMember	Original text (Japanese) 住友ファーマ株式会社
Address major shareholders	CurrentYearInstant_No3MajorShareholdersMember	Original text (Japanese) 大阪府大阪市中央区道修町二丁目６番８号
Name major shareholders	CurrentYearInstant_No4MajorShareholdersMember	Original text (Japanese) 株式会社日本カストディ銀行（信託口）
Address major shareholders	CurrentYearInstant_No4MajorShareholdersMember	Original text (Japanese) 東京都中央区晴海一丁目８番12号
Name major shareholders	CurrentYearInstant_No5MajorShareholdersMember	Original text (Japanese) GOLDMAN,SACHS & CO.REG(常任代理人　ゴールドマン・サックス証券株式会社)
Address major shareholders	CurrentYearInstant_No5MajorShareholdersMember	Original text (Japanese) 200 WEST STREET NEW YORK,NY,USA（東京都港区六本木六丁目10番１号）
Name major shareholders	CurrentYearInstant_No6MajorShareholdersMember	Original text (Japanese) 日本マスタートラスト信託銀行株式会社（信託口）
Address major shareholders	CurrentYearInstant_No6MajorShareholdersMember	Original text (Japanese) 東京都港区浜松町二丁目11番３号
Name major shareholders	CurrentYearInstant_No7MajorShareholdersMember	Text · Plus
Address major shareholders	CurrentYearInstant_No7MajorShareholdersMember	Text · Plus
Name major shareholders	CurrentYearInstant_No8MajorShareholdersMember	Original text (Japanese) 株式会社SBI証券
Address major shareholders	CurrentYearInstant_No8MajorShareholdersMember	Original text (Japanese) 東京都港区六本木一丁目６番１号
Name major shareholders	CurrentYearInstant_No9MajorShareholdersMember	Original text (Japanese) 野村信託銀行株式会社（信託口2052261）
Address major shareholders	CurrentYearInstant_No9MajorShareholdersMember	Original text (Japanese) 東京都千代田区大手町二丁目２番２号
Name major shareholders	CurrentYearInstant_No10MajorShareholdersMember	Original text (Japanese) 竹田　英樹
Address major shareholders	CurrentYearInstant_No10MajorShareholdersMember	Original text (Japanese) 兵庫県神戸市中央区
Issued shares voting rights (text)	FilingDateInstant	Text · Plus
Description issued shares voting rights	CurrentYearInstant_SharesWithNoVotingRightsMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithRestrictedVotingRightsTreasurySharesEtcMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithRestrictedVotingRightsOtherMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithFullVotingRightsTreasurySharesEtcMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithFullVotingRightsOtherMember	Original text (Japanese) 株主としての権利内容に何ら限定のない当社における標準となる株式。なお、単元株式数は100株であります。
Description issued shares voting rights	CurrentYearInstant_SharesLessThanOneUnitMember	－
Treasury shares etc (text)	FilingDateInstant	Text · Plus
Name of shareholder treasury shares etc	CurrentYearInstant_Row1Member	Original text (Japanese) 株式会社ヘリオス
Address of shareholder treasury shares etc	CurrentYearInstant_Row1Member	Original text (Japanese) 東京都千代田区有楽町一丁目７番１号
Classes of shares etc (text)	FilingDateInstant	Text · Plus
Acquisitions by resolution of shareholders meeting (text)	FilingDateInstant	Text · Plus
Acquisitions by resolution of board of directors meeting (text)	FilingDateInstant	Text · Plus
Acquisitions not based on resolution of shareholders meeting or board of directors meeting (text)	FilingDateInstant	Text · Plus
Disposals or holding of acquired treasury shares (text)	FilingDateInstant	Text · Plus
Dividend policy (text)	FilingDateInstant	Text · Plus
Overview of corporate governance (text)	FilingDateInstant	Text · Plus
Corporate governance company with nominating and other committees (text)	FilingDateInstant	Text · Plus
Information about officers (text)	FilingDateInstant	Text · Plus
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E31335-000KagimotoTadahisaMember	Original text (Japanese) 取締役
Name information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E31335-000KagimotoTadahisaMember	Original text (Japanese) 鍵本　忠尚
Date of birth information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E31335-000KagimotoTadahisaMember	1976-12-01
Career summary information about directors and corporate auditors (text)	FilingDateInstant_jpcrp030000-asr_E31335-000KagimotoTadahisaMember	Text · Plus
Term of office information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E31335-000KagimotoTadahisaMember	Original text (Japanese) （注）３
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E31335-000KashiiSeigoMember	Original text (Japanese) 取締役

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 20 of 20 passed

balance sheet identity	consolidated 2021-12-31	pass
balance sheet identity	consolidated 2022-12-31	pass rounding
balance sheet identity	non_consolidated 2021-12-31	pass
balance sheet identity	non_consolidated 2022-12-31	pass
dei present		pass
period resolution		pass
statement vs summary · net assets	non_consolidated 2020-12-31	pass
statement vs summary · net assets	non_consolidated 2021-12-31	pass
statement vs summary · net assets	non_consolidated 2022-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · operating cash flow	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · operating cash flow	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · revenue	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · revenue	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · revenue	non_consolidated 2022-01-01/2022-12-31	pass
statement vs summary · total assets	consolidated 2021-12-31	pass
statement vs summary · total assets	consolidated 2022-12-31	pass
statement vs summary · total assets	non_consolidated 2021-12-31	pass
statement vs summary · total assets	non_consolidated 2022-12-31	pass