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← SymBio Pharmaceuticals

Annual report

4582.TEDINET S100XNE5
Period2025-01-01 → 2025-12-31
Filed2026-03-24
StandardJapan GAAP
ConsolidatedYes
Data checks24 of 24 passed
Key figures · 130
MetricValuePeriodScopeSource row
Revenue¥1.3bn2025-01-01 → 2025-12-31Cons.Net sales
Revenue¥2.5bn2024-01-01 → 2024-12-31Cons.Net sales
Revenue¥5.6bn2023-01-01 → 2023-12-31vCons.Net sales (5-year summary)
Revenue¥10.0bn2022-01-01 → 2022-12-31vCons.Net sales (5-year summary)
Operating income−¥4.4bn2025-01-01 → 2025-12-31Cons.Operating income
Operating income−¥3.9bn2024-01-01 → 2024-12-31Cons.Operating income
Ordinary income−¥4.6bn2025-01-01 → 2025-12-31Cons.Ordinary income
Ordinary income−¥3.7bn2024-01-01 → 2024-12-31Cons.Ordinary income
Ordinary income−¥736m2023-01-01 → 2023-12-31vCons.Ordinary income loss (5-year summary)
Ordinary income¥2.0bn2022-01-01 → 2022-12-31vCons.Ordinary income loss (5-year summary)
Profit before tax−¥4.7bn2025-01-01 → 2025-12-31Cons.Income before income taxes
Profit before tax−¥3.8bn2024-01-01 → 2024-12-31Cons.Income before income taxes
Net income (owners)−¥4.8bn2025-01-01 → 2025-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥3.8bn2024-01-01 → 2024-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥2.0bn2023-01-01 → 2023-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income (owners)¥1.2bn2022-01-01 → 2022-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income−¥4.8bn2025-01-01 → 2025-12-31Cons.Profit loss
Net income−¥3.8bn2024-01-01 → 2024-12-31Cons.Profit loss
Total assets¥3.9bnat 2025-12-31Cons.Assets
Total assets¥5.0bnat 2024-12-31Cons.Assets
Total assets¥8.2bnat 2023-12-31vCons.Total assets (5-year summary)
Total assets¥10.4bnat 2022-12-31vCons.Total assets (5-year summary)
Total liabilities¥2.6bnat 2025-12-31Cons.Liabilities
Total liabilities¥771mat 2024-12-31Cons.Liabilities
Net assets / equity¥1.3bnat 2025-12-31Cons.Net assets
Net assets / equity¥4.2bnat 2024-12-31Cons.Net assets
Net assets / equity¥7.2bnat 2023-12-31vCons.Net assets
Net assets / equity¥8.5bnat 2022-12-31vCons.Net assets (5-year summary)
Cash and deposits¥2.9bnat 2025-12-31Cons.Cash and deposits
Cash and deposits¥4.0bnat 2024-12-31Cons.Cash and deposits
Cash & equivalents¥2.9bnat 2025-12-31Cons.Cash and cash equivalents
Cash & equivalents¥4.0bnat 2024-12-31Cons.Cash and cash equivalents
Cash & equivalents¥6.5bnat 2023-12-31vCons.Cash and cash equivalents
Cash & equivalents¥6.3bnat 2022-12-31vCons.Cash and cash equivalents (5-year summary)
Operating cash flow−¥4.6bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥3.4bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥195m2023-01-01 → 2023-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Operating cash flow¥1.6bn2022-01-01 → 2022-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Investing cash flow−¥76m2025-01-01 → 2025-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥4m2024-01-01 → 2024-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥377m2023-01-01 → 2023-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Investing cash flow−¥47m2022-01-01 → 2022-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Financing cash flow¥3.6bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥708m2024-01-01 → 2024-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥680m2023-01-01 → 2023-12-31vCons.Net cash provided by used in financing activities (5-year summary)
Financing cash flow¥628m2022-01-01 → 2022-12-31vCons.Net cash provided by used in financing activities (5-year summary)
EPS (basic)¥-95.122025-01-01 → 2025-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-852024-01-01 → 2024-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-49.192023-01-01 → 2023-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (basic)¥30.22022-01-01 → 2022-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (diluted)¥29.772022-01-01 → 2022-12-31vCons.Diluted earnings per share (5-year summary)
Net assets per share¥15.54at 2025-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥84.66at 2024-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥164.32at 2023-12-31vCons.Net assets per share (5-year summary)
Net assets per share¥204.83at 2022-12-31vCons.Net assets per share (5-year summary)
Equity ratio23.9%at 2025-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio78.1%at 2024-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio84.9%at 2023-12-31vCons.Equity to asset ratio (5-year summary)
Equity ratio77.6%at 2022-12-31vCons.Equity to asset ratio (5-year summary)
ROE14.6%2022-01-01 → 2022-12-31vCons.Rate of return on equity (5-year summary)
Employees91at 2025-12-31Cons.Number of employees
Employees108at 2024-12-31Cons.Number of employees
Employees109at 2023-12-31vCons.Number of employees
Employees122at 2022-12-31vCons.Number of employees
Revenue¥1.3bn2025-01-01 → 2025-12-31StandaloneNet sales
Revenue¥2.5bn2024-01-01 → 2024-12-31StandaloneNet sales
Revenue¥5.6bn2023-01-01 → 2023-12-31vStandaloneNet sales (5-year summary)
Revenue¥10.0bn2022-01-01 → 2022-12-31vStandaloneNet sales (5-year summary)
Revenue¥8.3bn2021-01-01 → 2021-12-31dStandaloneNet sales (5-year summary)
Operating income−¥4.6bn2025-01-01 → 2025-12-31StandaloneOperating income
Operating income−¥4.0bn2024-01-01 → 2024-12-31StandaloneOperating income
Ordinary income−¥4.8bn2025-01-01 → 2025-12-31StandaloneOrdinary income
Ordinary income−¥3.8bn2024-01-01 → 2024-12-31StandaloneOrdinary income
Ordinary income−¥774m2023-01-01 → 2023-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥2.0bn2022-01-01 → 2022-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥1.0bn2021-01-01 → 2021-12-31dStandaloneOrdinary income loss (5-year summary)
Profit before tax−¥4.9bn2025-01-01 → 2025-12-31StandaloneIncome before income taxes
Profit before tax−¥3.9bn2024-01-01 → 2024-12-31StandaloneIncome before income taxes
Net income−¥4.9bn2025-01-01 → 2025-12-31StandaloneProfit loss
Net income−¥3.9bn2024-01-01 → 2024-12-31StandaloneProfit loss
Net income−¥2.0bn2023-01-01 → 2023-12-31vStandaloneNet income loss (5-year summary)
Net income¥1.2bn2022-01-01 → 2022-12-31vStandaloneNet income loss (5-year summary)
Net income¥2.0bn2021-01-01 → 2021-12-31dStandaloneNet income loss (5-year summary)
Total assets¥3.6bnat 2025-12-31StandaloneAssets
Total assets¥4.7bnat 2024-12-31StandaloneAssets
Total assets¥8.2bnat 2023-12-31vStandaloneTotal assets (5-year summary)
Total assets¥10.4bnat 2022-12-31vStandaloneTotal assets (5-year summary)
Total assets¥8.5bnat 2021-12-31dStandaloneTotal assets (5-year summary)
Total liabilities¥2.5bnat 2025-12-31StandaloneLiabilities
Total liabilities¥639mat 2024-12-31StandaloneLiabilities
Net assets / equity¥1.0bnat 2025-12-31StandaloneNet assets
Net assets / equity¥4.1bnat 2024-12-31StandaloneNet assets
Net assets / equity¥7.2bnat 2023-12-31vStandaloneNet assets
Net assets / equity¥8.5bnat 2022-12-31vStandaloneNet assets (5-year summary)
Net assets / equity¥6.7bnat 2021-12-31dStandaloneNet assets (5-year summary)
Cash and deposits¥2.5bnat 2025-12-31StandaloneCash and deposits
Cash and deposits¥3.7bnat 2024-12-31StandaloneCash and deposits
Cash & equivalents¥3.9bnat 2021-12-31dStandaloneCash and cash equivalents (5-year summary)
Operating cash flow¥140m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in operating activities (5-year summary)
Investing cash flow−¥71m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in investing activities (5-year summary)
Financing cash flow−¥72m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in financing activities (5-year summary)
EPS (basic)¥-97.622025-01-01 → 2025-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-872024-01-01 → 2024-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-49.792023-01-01 → 2023-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥30.372022-01-01 → 2022-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥53.042021-01-01 → 2021-12-31dStandaloneBasic earnings loss per share (5-year summary)
EPS (diluted)¥29.952022-01-01 → 2022-12-31vStandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥52.322021-01-01 → 2021-12-31dStandaloneDiluted earnings per share (5-year summary)
Net assets per share¥11.38at 2025-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥82.12at 2024-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥164.02at 2023-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥204.95at 2022-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥162.26at 2021-12-31dStandaloneNet assets per share (5-year summary)
Equity ratio19.0%at 2025-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio79.7%at 2024-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio84.6%at 2023-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio77.8%at 2022-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio73.7%at 2021-12-31dStandaloneEquity to asset ratio (5-year summary)
ROE16.6%2022-01-01 → 2022-12-31vStandaloneRate of return on equity (5-year summary)
ROE39.6%2021-01-01 → 2021-12-31dStandaloneRate of return on equity (5-year summary)
Shares issued59,567,080at 2025-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued45,928,856at 2024-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued42,278,081at 2023-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued39,603,606at 2022-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued38,457,206at 2021-12-31dStandaloneTotal number of issued shares (5-year summary)
Employees86at 2025-12-31StandaloneNumber of employees
Employees101at 2024-12-31StandaloneNumber of employees
Employees103at 2023-12-31vStandaloneNumber of employees
Employees118at 2022-12-31vStandaloneNumber of employees
Employees141at 2021-12-31dStandaloneNumber of employees

Periods use the dates stated in the filing. d = earlier-year period dated by calendar; v = that date confirmed by the company's own earlier filing.

Segments · 1
SegmentItemPeriodValue
Research And Development Manufacturing And Sales Of Pharmaceuticals Etc And Related Businessreportable segmentemployeesat 2025-12-3191 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,228
ItemContextValueUnit
Other caCurrentYearInstant_NonConsolidatedMember51201000JPY
Current assetsPrior1YearInstant_NonConsolidatedMember4675267000JPY
Current assetsCurrentYearInstant_NonConsolidatedMember3529707000JPY
Stocks of subsidiaries and affiliatesPrior1YearInstant_NonConsolidatedMember0JPY
Stocks of subsidiaries and affiliatesCurrentYearInstant_NonConsolidatedMember15000JPY
Lease and guarantee depositsPrior1YearInstant_NonConsolidatedMember44102000JPY
Lease and guarantee depositsCurrentYearInstant_NonConsolidatedMember37349000JPY
Investments and other assetsPrior1YearInstant_NonConsolidatedMember44102000JPY
Investments and other assetsCurrentYearInstant_NonConsolidatedMember37365000JPY
Noncurrent assetsPrior1YearInstant_NonConsolidatedMember44102000JPY
Noncurrent assetsCurrentYearInstant_NonConsolidatedMember37365000JPY
AssetsPrior1YearInstant_NonConsolidatedMember4719369000JPY
AssetsCurrentYearInstant_NonConsolidatedMember3567072000JPY
Accounts payable otherPrior1YearInstant_NonConsolidatedMember503669000JPY
Accounts payable otherCurrentYearInstant_NonConsolidatedMember424557000JPY
Income taxes payablePrior1YearInstant_NonConsolidatedMember102006000JPY
Income taxes payableCurrentYearInstant_NonConsolidatedMember109516000JPY
Current portion of bondsPrior1YearInstant_NonConsolidatedMember－JPY
Current portion of bondsCurrentYearInstant_NonConsolidatedMember682500000JPY
Other clPrior1YearInstant_NonConsolidatedMember28310000JPY
Other clCurrentYearInstant_NonConsolidatedMember21045000JPY
Current liabilitiesPrior1YearInstant_NonConsolidatedMember633987000JPY
Current liabilitiesCurrentYearInstant_NonConsolidatedMember1237619000JPY
Convertible bond type bonds with subscription rights to sharesPrior1YearInstant_NonConsolidatedMember－JPY
Convertible bond type bonds with subscription rights to sharesCurrentYearInstant_NonConsolidatedMember1300000000JPY
Provision for retirement benefitsPrior1YearInstant_NonConsolidatedMember4603000JPY
Provision for retirement benefitsCurrentYearInstant_NonConsolidatedMember4911000JPY
Noncurrent liabilitiesPrior1YearInstant_NonConsolidatedMember4603000JPY
Noncurrent liabilitiesCurrentYearInstant_NonConsolidatedMember1304911000JPY
LiabilitiesPrior1YearInstant_NonConsolidatedMember638590000JPY
LiabilitiesCurrentYearInstant_NonConsolidatedMember2542530000JPY
Capital stockPrior1YearInstant_NonConsolidatedMember18336841000JPY
Capital stockCurrentYearInstant_NonConsolidatedMember19244128000JPY
Legal capital surplusPrior1YearInstant_NonConsolidatedMember18306841000JPY
Legal capital surplusCurrentYearInstant_NonConsolidatedMember19214128000JPY
Other capital surplusPrior1YearInstant_NonConsolidatedMember4872000JPY
Other capital surplusCurrentYearInstant_NonConsolidatedMember4837000JPY
Capital surplusPrior1YearInstant_NonConsolidatedMember18311713000JPY
Capital surplusCurrentYearInstant_NonConsolidatedMember19218965000JPY
Retained earnings brought forwardPrior1YearInstant_NonConsolidatedMember-32794671000JPY
Retained earnings brought forwardCurrentYearInstant_NonConsolidatedMember-37696551000JPY
Retained earningsPrior1YearInstant_NonConsolidatedMember-32794671000JPY
Retained earningsCurrentYearInstant_NonConsolidatedMember-37696551000JPY
Treasury stockPrior1YearInstant_NonConsolidatedMember-89863000JPY
Treasury stockCurrentYearInstant_NonConsolidatedMember-89870000JPY
Shareholders equityPrior1YearInstant_NonConsolidatedMember3764020000JPY
Shareholders equityCurrentYearInstant_NonConsolidatedMember676671000JPY
Subscription rights to sharesPrior1YearInstant_NonConsolidatedMember316758000JPY
Subscription rights to sharesCurrentYearInstant_NonConsolidatedMember347869000JPY
Net assetsPrior1YearInstant_NonConsolidatedMember4080779000JPY

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 24 of 24 passed
balance sheet identityconsolidated 2024-12-31pass rounding
balance sheet identityconsolidated 2025-12-31pass
balance sheet identitynon_consolidated 2024-12-31pass
balance sheet identitynon_consolidated 2025-12-31pass rounding
dei present pass
period resolution pass
statement vs summary · net assetsconsolidated 2023-12-31pass
statement vs summary · net assetsconsolidated 2024-12-31pass
statement vs summary · net assetsconsolidated 2025-12-31pass
statement vs summary · net assetsnon_consolidated 2023-12-31pass
statement vs summary · net assetsnon_consolidated 2024-12-31pass
statement vs summary · net assetsnon_consolidated 2025-12-31pass
statement vs summary · net income attributable to parentconsolidated 2024-01-01/2024-12-31pass
statement vs summary · net income attributable to parentconsolidated 2025-01-01/2025-12-31pass
statement vs summary · operating cash flowconsolidated 2024-01-01/2024-12-31pass
statement vs summary · operating cash flowconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenueconsolidated 2024-01-01/2024-12-31pass
statement vs summary · revenueconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenuenon_consolidated 2024-01-01/2024-12-31pass
statement vs summary · revenuenon_consolidated 2025-01-01/2025-12-31pass
statement vs summary · total assetsconsolidated 2024-12-31pass
statement vs summary · total assetsconsolidated 2025-12-31pass
statement vs summary · total assetsnon_consolidated 2024-12-31pass
statement vs summary · total assetsnon_consolidated 2025-12-31pass