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← SymBio Pharmaceuticals

Annual report

4582.TEDINET S100XNE5
Period2025-01-01 → 2025-12-31
Filed2026-03-24
StandardJapan GAAP
ConsolidatedYes
Data checks24 of 24 passed
Key figures · 130
MetricValuePeriodScopeSource row
Revenue¥1.3bn2025-01-01 → 2025-12-31Cons.Net sales
Revenue¥2.5bn2024-01-01 → 2024-12-31Cons.Net sales
Revenue¥5.6bn2023-01-01 → 2023-12-31vCons.Net sales (5-year summary)
Revenue¥10.0bn2022-01-01 → 2022-12-31vCons.Net sales (5-year summary)
Operating income−¥4.4bn2025-01-01 → 2025-12-31Cons.Operating income
Operating income−¥3.9bn2024-01-01 → 2024-12-31Cons.Operating income
Ordinary income−¥4.6bn2025-01-01 → 2025-12-31Cons.Ordinary income
Ordinary income−¥3.7bn2024-01-01 → 2024-12-31Cons.Ordinary income
Ordinary income−¥736m2023-01-01 → 2023-12-31vCons.Ordinary income loss (5-year summary)
Ordinary income¥2.0bn2022-01-01 → 2022-12-31vCons.Ordinary income loss (5-year summary)
Profit before tax−¥4.7bn2025-01-01 → 2025-12-31Cons.Income before income taxes
Profit before tax−¥3.8bn2024-01-01 → 2024-12-31Cons.Income before income taxes
Net income (owners)−¥4.8bn2025-01-01 → 2025-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥3.8bn2024-01-01 → 2024-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥2.0bn2023-01-01 → 2023-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income (owners)¥1.2bn2022-01-01 → 2022-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income−¥4.8bn2025-01-01 → 2025-12-31Cons.Profit loss
Net income−¥3.8bn2024-01-01 → 2024-12-31Cons.Profit loss
Total assets¥3.9bnat 2025-12-31Cons.Assets
Total assets¥5.0bnat 2024-12-31Cons.Assets
Total assets¥8.2bnat 2023-12-31vCons.Total assets (5-year summary)
Total assets¥10.4bnat 2022-12-31vCons.Total assets (5-year summary)
Total liabilities¥2.6bnat 2025-12-31Cons.Liabilities
Total liabilities¥771mat 2024-12-31Cons.Liabilities
Net assets / equity¥1.3bnat 2025-12-31Cons.Net assets
Net assets / equity¥4.2bnat 2024-12-31Cons.Net assets
Net assets / equity¥7.2bnat 2023-12-31vCons.Net assets
Net assets / equity¥8.5bnat 2022-12-31vCons.Net assets (5-year summary)
Cash and deposits¥2.9bnat 2025-12-31Cons.Cash and deposits
Cash and deposits¥4.0bnat 2024-12-31Cons.Cash and deposits
Cash & equivalents¥2.9bnat 2025-12-31Cons.Cash and cash equivalents
Cash & equivalents¥4.0bnat 2024-12-31Cons.Cash and cash equivalents
Cash & equivalents¥6.5bnat 2023-12-31vCons.Cash and cash equivalents
Cash & equivalents¥6.3bnat 2022-12-31vCons.Cash and cash equivalents (5-year summary)
Operating cash flow−¥4.6bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥3.4bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥195m2023-01-01 → 2023-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Operating cash flow¥1.6bn2022-01-01 → 2022-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Investing cash flow−¥76m2025-01-01 → 2025-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥4m2024-01-01 → 2024-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥377m2023-01-01 → 2023-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Investing cash flow−¥47m2022-01-01 → 2022-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Financing cash flow¥3.6bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥708m2024-01-01 → 2024-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥680m2023-01-01 → 2023-12-31vCons.Net cash provided by used in financing activities (5-year summary)
Financing cash flow¥628m2022-01-01 → 2022-12-31vCons.Net cash provided by used in financing activities (5-year summary)
EPS (basic)¥-95.122025-01-01 → 2025-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-852024-01-01 → 2024-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-49.192023-01-01 → 2023-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (basic)¥30.22022-01-01 → 2022-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (diluted)¥29.772022-01-01 → 2022-12-31vCons.Diluted earnings per share (5-year summary)
Net assets per share¥15.54at 2025-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥84.66at 2024-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥164.32at 2023-12-31vCons.Net assets per share (5-year summary)
Net assets per share¥204.83at 2022-12-31vCons.Net assets per share (5-year summary)
Equity ratio23.9%at 2025-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio78.1%at 2024-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio84.9%at 2023-12-31vCons.Equity to asset ratio (5-year summary)
Equity ratio77.6%at 2022-12-31vCons.Equity to asset ratio (5-year summary)
ROE14.6%2022-01-01 → 2022-12-31vCons.Rate of return on equity (5-year summary)
Employees91at 2025-12-31Cons.Number of employees
Employees108at 2024-12-31Cons.Number of employees
Employees109at 2023-12-31vCons.Number of employees
Employees122at 2022-12-31vCons.Number of employees
Revenue¥1.3bn2025-01-01 → 2025-12-31StandaloneNet sales
Revenue¥2.5bn2024-01-01 → 2024-12-31StandaloneNet sales
Revenue¥5.6bn2023-01-01 → 2023-12-31vStandaloneNet sales (5-year summary)
Revenue¥10.0bn2022-01-01 → 2022-12-31vStandaloneNet sales (5-year summary)
Revenue¥8.3bn2021-01-01 → 2021-12-31dStandaloneNet sales (5-year summary)
Operating income−¥4.6bn2025-01-01 → 2025-12-31StandaloneOperating income
Operating income−¥4.0bn2024-01-01 → 2024-12-31StandaloneOperating income
Ordinary income−¥4.8bn2025-01-01 → 2025-12-31StandaloneOrdinary income
Ordinary income−¥3.8bn2024-01-01 → 2024-12-31StandaloneOrdinary income
Ordinary income−¥774m2023-01-01 → 2023-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥2.0bn2022-01-01 → 2022-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥1.0bn2021-01-01 → 2021-12-31dStandaloneOrdinary income loss (5-year summary)
Profit before tax−¥4.9bn2025-01-01 → 2025-12-31StandaloneIncome before income taxes
Profit before tax−¥3.9bn2024-01-01 → 2024-12-31StandaloneIncome before income taxes
Net income−¥4.9bn2025-01-01 → 2025-12-31StandaloneProfit loss
Net income−¥3.9bn2024-01-01 → 2024-12-31StandaloneProfit loss
Net income−¥2.0bn2023-01-01 → 2023-12-31vStandaloneNet income loss (5-year summary)
Net income¥1.2bn2022-01-01 → 2022-12-31vStandaloneNet income loss (5-year summary)
Net income¥2.0bn2021-01-01 → 2021-12-31dStandaloneNet income loss (5-year summary)
Total assets¥3.6bnat 2025-12-31StandaloneAssets
Total assets¥4.7bnat 2024-12-31StandaloneAssets
Total assets¥8.2bnat 2023-12-31vStandaloneTotal assets (5-year summary)
Total assets¥10.4bnat 2022-12-31vStandaloneTotal assets (5-year summary)
Total assets¥8.5bnat 2021-12-31dStandaloneTotal assets (5-year summary)
Total liabilities¥2.5bnat 2025-12-31StandaloneLiabilities
Total liabilities¥639mat 2024-12-31StandaloneLiabilities
Net assets / equity¥1.0bnat 2025-12-31StandaloneNet assets
Net assets / equity¥4.1bnat 2024-12-31StandaloneNet assets
Net assets / equity¥7.2bnat 2023-12-31vStandaloneNet assets
Net assets / equity¥8.5bnat 2022-12-31vStandaloneNet assets (5-year summary)
Net assets / equity¥6.7bnat 2021-12-31dStandaloneNet assets (5-year summary)
Cash and deposits¥2.5bnat 2025-12-31StandaloneCash and deposits
Cash and deposits¥3.7bnat 2024-12-31StandaloneCash and deposits
Cash & equivalents¥3.9bnat 2021-12-31dStandaloneCash and cash equivalents (5-year summary)
Operating cash flow¥140m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in operating activities (5-year summary)
Investing cash flow−¥71m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in investing activities (5-year summary)
Financing cash flow−¥72m2021-01-01 → 2021-12-31dStandaloneNet cash provided by used in financing activities (5-year summary)
EPS (basic)¥-97.622025-01-01 → 2025-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-872024-01-01 → 2024-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-49.792023-01-01 → 2023-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥30.372022-01-01 → 2022-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥53.042021-01-01 → 2021-12-31dStandaloneBasic earnings loss per share (5-year summary)
EPS (diluted)¥29.952022-01-01 → 2022-12-31vStandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥52.322021-01-01 → 2021-12-31dStandaloneDiluted earnings per share (5-year summary)
Net assets per share¥11.38at 2025-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥82.12at 2024-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥164.02at 2023-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥204.95at 2022-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥162.26at 2021-12-31dStandaloneNet assets per share (5-year summary)
Equity ratio19.0%at 2025-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio79.7%at 2024-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio84.6%at 2023-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio77.8%at 2022-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio73.7%at 2021-12-31dStandaloneEquity to asset ratio (5-year summary)
ROE16.6%2022-01-01 → 2022-12-31vStandaloneRate of return on equity (5-year summary)
ROE39.6%2021-01-01 → 2021-12-31dStandaloneRate of return on equity (5-year summary)
Shares issued59,567,080at 2025-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued45,928,856at 2024-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued42,278,081at 2023-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued39,603,606at 2022-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued38,457,206at 2021-12-31dStandaloneTotal number of issued shares (5-year summary)
Employees86at 2025-12-31StandaloneNumber of employees
Employees101at 2024-12-31StandaloneNumber of employees
Employees103at 2023-12-31vStandaloneNumber of employees
Employees118at 2022-12-31vStandaloneNumber of employees
Employees141at 2021-12-31dStandaloneNumber of employees

Periods use the dates stated in the filing. d = earlier-year period dated by calendar; v = that date confirmed by the company's own earlier filing.

Segments · 1
SegmentItemPeriodValue
Research And Development Manufacturing And Sales Of Pharmaceuticals Etc And Related Businessreportable segmentemployeesat 2025-12-3191 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,228
ItemContextValueUnit
Gain on reversal of subscription rights to shares ope cfPrior1YearDuration-14298000JPY
Gain on reversal of subscription rights to shares ope cfCurrentYearDuration-8536000JPY
Decrease increase in notes and accounts receivable trade ope cfPrior1YearDuration489940000JPY
Decrease increase in notes and accounts receivable trade ope cfCurrentYearDuration163476000JPY
Decrease increase in inventories ope cfPrior1YearDuration54663000JPY
Decrease increase in inventories ope cfCurrentYearDuration-50027000JPY
Decrease increase in prepaid expenses ope cfPrior1YearDuration-71492000JPY
Decrease increase in prepaid expenses ope cfCurrentYearDuration23698000JPY
Decrease increase in consumption taxes receivable payable ope cfPrior1YearDuration-65693000JPY
Decrease increase in consumption taxes receivable payable ope cfCurrentYearDuration-27652000JPY
Decrease increase in other current assets ope cfPrior1YearDuration73427000JPY
Decrease increase in other current assets ope cfCurrentYearDuration-128061000JPY
Increase decrease in accounts payable other ope cfPrior1YearDuration-215972000JPY
Increase decrease in accounts payable other ope cfCurrentYearDuration-169380000JPY
Increase decrease in other current liabilities ope cfPrior1YearDuration14091000JPY
Increase decrease in other current liabilities ope cfCurrentYearDuration244000JPY
Other net ope cfPrior1YearDuration-3799000JPY
Other net ope cfCurrentYearDuration249000JPY
Subtotal ope cfPrior1YearDuration-3476377000JPY
Subtotal ope cfCurrentYearDuration-4541949000JPY
Interest and dividends income received ope cf inv cfPrior1YearDuration43814000JPY
Interest and dividends income received ope cf inv cfCurrentYearDuration4195000JPY
Proceeds from insurance income ope cfPrior1YearDuration－JPY
Proceeds from insurance income ope cfCurrentYearDuration24394000JPY
Interest expenses paid ope cf fin cfPrior1YearDuration－JPY
Interest expenses paid ope cf fin cfCurrentYearDuration-39238000JPY
Commitment fee paid ope cfPrior1YearDuration-23953000JPY
Commitment fee paid ope cfCurrentYearDuration-10373000JPY
Income taxes paid refund ope cfPrior1YearDuration39997000JPY
Income taxes paid refund ope cfCurrentYearDuration-12597000JPY
Net cash provided by used in operating activitiesPrior1YearDuration-3416518000JPY
Net cash provided by used in operating activitiesCurrentYearDuration-4575568000JPY
Purchase of property plant and equipment inv cfPrior1YearDuration-19816000JPY
Purchase of property plant and equipment inv cfCurrentYearDuration－JPY
Purchase of intangible assets inv cfPrior1YearDuration-27061000JPY
Purchase of intangible assets inv cfCurrentYearDuration-82472000JPY
Proceeds from collection of lease and guarantee deposits inv cfPrior1YearDuration42923000JPY
Proceeds from collection of lease and guarantee deposits inv cfCurrentYearDuration6571000JPY
Purchase of investments in subsidiaries inv cfPrior1YearDuration－JPY
Purchase of investments in subsidiaries inv cfCurrentYearDuration-15000JPY
Net cash provided by used in investment activitiesPrior1YearDuration-3955000JPY
Net cash provided by used in investment activitiesCurrentYearDuration-75916000JPY
Proceeds from issuance of stock resulting from exercise of subscription rights to shares fin cfPrior1YearDuration50000JPY
Proceeds from issuance of stock resulting from exercise of subscription rights to shares fin cfCurrentYearDuration1256210000JPY
Proceeds from issuance of bonds with subscription rights to shares fin cfPrior1YearDuration－JPY
Proceeds from issuance of bonds with subscription rights to shares fin cfCurrentYearDuration1689719000JPY
Proceeds from issuance of subscription rights to shares fin cfPrior1YearDuration－JPY
Proceeds from issuance of subscription rights to shares fin cfCurrentYearDuration3300000JPY
Proceeds from issuance of common stock fin cfPrior1YearDuration728850000JPY
Proceeds from issuance of common stock fin cfCurrentYearDuration－JPY

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 24 of 24 passed
balance sheet identityconsolidated 2024-12-31pass rounding
balance sheet identityconsolidated 2025-12-31pass
balance sheet identitynon_consolidated 2024-12-31pass
balance sheet identitynon_consolidated 2025-12-31pass rounding
dei present pass
period resolution pass
statement vs summary · net assetsconsolidated 2023-12-31pass
statement vs summary · net assetsconsolidated 2024-12-31pass
statement vs summary · net assetsconsolidated 2025-12-31pass
statement vs summary · net assetsnon_consolidated 2023-12-31pass
statement vs summary · net assetsnon_consolidated 2024-12-31pass
statement vs summary · net assetsnon_consolidated 2025-12-31pass
statement vs summary · net income attributable to parentconsolidated 2024-01-01/2024-12-31pass
statement vs summary · net income attributable to parentconsolidated 2025-01-01/2025-12-31pass
statement vs summary · operating cash flowconsolidated 2024-01-01/2024-12-31pass
statement vs summary · operating cash flowconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenueconsolidated 2024-01-01/2024-12-31pass
statement vs summary · revenueconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenuenon_consolidated 2024-01-01/2024-12-31pass
statement vs summary · revenuenon_consolidated 2025-01-01/2025-12-31pass
statement vs summary · total assetsconsolidated 2024-12-31pass
statement vs summary · total assetsconsolidated 2025-12-31pass
statement vs summary · total assetsnon_consolidated 2024-12-31pass
statement vs summary · total assetsnon_consolidated 2025-12-31pass