Annual report

Period2025-01-01 → 2025-12-31
Filed2026-03-25
StandardJapan GAAP
ConsolidatedYes
Data checks20 of 20 passed
Key figures · 125
MetricValuePeriodScopeSource row
Operating income−¥5.1bn2025-01-01 → 2025-12-31Cons.Operating income
Operating income−¥9.1bn2024-01-01 → 2024-12-31Cons.Operating income
Ordinary income−¥5.3bn2025-01-01 → 2025-12-31Cons.Ordinary income
Ordinary income−¥7.5bn2024-01-01 → 2024-12-31Cons.Ordinary income
Ordinary income−¥5.7bn2023-01-01 → 2023-12-31vCons.Ordinary income loss (5-year summary)
Ordinary income−¥14.6bn2022-01-01 → 2022-12-31vCons.Ordinary income loss (5-year summary)
Ordinary income−¥13.6bn2021-01-01 → 2021-12-31dCons.Ordinary income loss (5-year summary)
Profit before tax−¥5.2bn2025-01-01 → 2025-12-31Cons.Income before income taxes
Profit before tax−¥27.6bn2024-01-01 → 2024-12-31Cons.Income before income taxes
Net income (owners)−¥5.1bn2025-01-01 → 2025-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥28.1bn2024-01-01 → 2024-12-31Cons.Profit loss attributable to owners of parent
Net income (owners)−¥7.4bn2023-01-01 → 2023-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income (owners)−¥14.7bn2022-01-01 → 2022-12-31vCons.Profit loss attributable to owners of parent (5-year summary)
Net income (owners)−¥13.7bn2021-01-01 → 2021-12-31dCons.Profit loss attributable to owners of parent (5-year summary)
Net income−¥5.1bn2025-01-01 → 2025-12-31Cons.Profit loss
Net income−¥28.1bn2024-01-01 → 2024-12-31Cons.Profit loss
Total assets¥5.4bnat 2025-12-31Cons.Assets
Total assets¥4.7bnat 2024-12-31Cons.Assets
Total assets¥28.9bnat 2023-12-31vCons.Total assets (5-year summary)
Total assets¥38.8bnat 2022-12-31vCons.Total assets (5-year summary)
Total assets¥45.5bnat 2021-12-31dCons.Total assets (5-year summary)
Total liabilities¥2.3bnat 2025-12-31Cons.Liabilities
Total liabilities¥2.5bnat 2024-12-31Cons.Liabilities
Net assets / equity¥3.1bnat 2025-12-31Cons.Net assets
Net assets / equity¥2.2bnat 2024-12-31Cons.Net assets
Net assets / equity¥26.1bnat 2023-12-31vCons.Net assets
Net assets / equity¥30.4bnat 2022-12-31vCons.Net assets (5-year summary)
Net assets / equity¥38.6bnat 2021-12-31dCons.Net assets (5-year summary)
Cash and deposits¥1.9bnat 2025-12-31Cons.Cash and deposits
Cash and deposits¥1.7bnat 2024-12-31Cons.Cash and deposits
Cash & equivalents¥1.8bnat 2025-12-31Cons.Cash and cash equivalents
Cash & equivalents¥1.6bnat 2024-12-31Cons.Cash and cash equivalents
Cash & equivalents¥4.1bnat 2023-12-31vCons.Cash and cash equivalents
Cash & equivalents¥11.0bnat 2022-12-31vCons.Cash and cash equivalents (5-year summary)
Cash & equivalents¥17.8bnat 2021-12-31dCons.Cash and cash equivalents (5-year summary)
Operating cash flow−¥5.8bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥6.6bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in operating activities
Operating cash flow−¥8.7bn2023-01-01 → 2023-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Operating cash flow−¥11.2bn2022-01-01 → 2022-12-31vCons.Net cash provided by used in operating activities (5-year summary)
Operating cash flow−¥11.4bn2021-01-01 → 2021-12-31dCons.Net cash provided by used in operating activities (5-year summary)
Investing cash flow¥19m2025-01-01 → 2025-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥131m2024-01-01 → 2024-12-31Cons.Net cash provided by used in investment activities
Investing cash flow−¥357m2023-01-01 → 2023-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Investing cash flow−¥97m2022-01-01 → 2022-12-31vCons.Net cash provided by used in investing activities (5-year summary)
Investing cash flow−¥155m2021-01-01 → 2021-12-31dCons.Net cash provided by used in investing activities (5-year summary)
Financing cash flow¥5.9bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥4.2bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in financing activities
Financing cash flow¥2.0bn2023-01-01 → 2023-12-31vCons.Net cash provided by used in financing activities (5-year summary)
Financing cash flow¥3.6bn2022-01-01 → 2022-12-31vCons.Net cash provided by used in financing activities (5-year summary)
Financing cash flow¥17.4bn2021-01-01 → 2021-12-31dCons.Net cash provided by used in financing activities (5-year summary)
EPS (basic)¥-14.442025-01-01 → 2025-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-119.532024-01-01 → 2024-12-31Cons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-39.292023-01-01 → 2023-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-94.292022-01-01 → 2022-12-31vCons.Basic earnings loss per share (5-year summary)
EPS (basic)¥-92.862021-01-01 → 2021-12-31dCons.Basic earnings loss per share (5-year summary)
Net assets per share¥7.67at 2025-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥7.17at 2024-12-31Cons.Net assets per share (5-year summary)
Net assets per share¥131.04at 2023-12-31vCons.Net assets per share (5-year summary)
Net assets per share¥169.77at 2022-12-31vCons.Net assets per share (5-year summary)
Net assets per share¥251.81at 2021-12-31dCons.Net assets per share (5-year summary)
Equity ratio55.2%at 2025-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio44.0%at 2024-12-31Cons.Equity to asset ratio (5-year summary)
Equity ratio90.0%at 2023-12-31vCons.Equity to asset ratio (5-year summary)
Equity ratio78.1%at 2022-12-31vCons.Equity to asset ratio (5-year summary)
Equity ratio84.8%at 2021-12-31dCons.Equity to asset ratio (5-year summary)
Employees56at 2025-12-31Cons.Number of employees
Employees55at 2024-12-31Cons.Number of employees
Employees145at 2023-12-31vCons.Number of employees
Employees138at 2022-12-31vCons.Number of employees
Employees131at 2021-12-31dCons.Number of employees
Operating income−¥4.4bn2025-01-01 → 2025-12-31StandaloneOperating income
Operating income−¥4.9bn2024-01-01 → 2024-12-31StandaloneOperating income
Ordinary income−¥4.5bn2025-01-01 → 2025-12-31StandaloneOrdinary income
Ordinary income−¥3.1bn2024-01-01 → 2024-12-31StandaloneOrdinary income
Ordinary income¥2.0bn2023-01-01 → 2023-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income−¥8.0bn2022-01-01 → 2022-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income−¥7.9bn2021-01-01 → 2021-12-31dStandaloneOrdinary income loss (5-year summary)
Profit before tax−¥5.7bn2025-01-01 → 2025-12-31StandaloneIncome before income taxes
Profit before tax−¥39.3bn2024-01-01 → 2024-12-31StandaloneIncome before income taxes
Net income−¥5.7bn2025-01-01 → 2025-12-31StandaloneProfit loss
Net income−¥39.3bn2024-01-01 → 2024-12-31StandaloneProfit loss
Net income¥1.1bn2023-01-01 → 2023-12-31vStandaloneNet income loss (5-year summary)
Net income−¥8.1bn2022-01-01 → 2022-12-31vStandaloneNet income loss (5-year summary)
Net income−¥8.1bn2021-01-01 → 2021-12-31dStandaloneNet income loss (5-year summary)
Total assets¥4.4bnat 2025-12-31StandaloneAssets
Total assets¥3.7bnat 2024-12-31StandaloneAssets
Total assets¥38.7bnat 2023-12-31vStandaloneTotal assets (5-year summary)
Total assets¥40.7bnat 2022-12-31vStandaloneTotal assets (5-year summary)
Total assets¥44.9bnat 2021-12-31dStandaloneTotal assets (5-year summary)
Total liabilities¥1.8bnat 2025-12-31StandaloneLiabilities
Total liabilities¥1.3bnat 2024-12-31StandaloneLiabilities
Net assets / equity¥2.7bnat 2025-12-31StandaloneNet assets
Net assets / equity¥2.4bnat 2024-12-31StandaloneNet assets
Net assets / equity¥37.3bnat 2023-12-31vStandaloneNet assets
Net assets / equity¥34.1bnat 2022-12-31vStandaloneNet assets (5-year summary)
Net assets / equity¥38.7bnat 2021-12-31dStandaloneNet assets (5-year summary)
Cash and deposits¥1.2bnat 2025-12-31StandaloneCash and deposits
Cash and deposits¥1.1bnat 2024-12-31StandaloneCash and deposits
EPS (basic)¥-15.952025-01-01 → 2025-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-167.032024-01-01 → 2024-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥5.642023-01-01 → 2023-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-522022-01-01 → 2022-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥-54.912021-01-01 → 2021-12-31dStandaloneBasic earnings loss per share (5-year summary)
EPS (diluted)¥5.492023-01-01 → 2023-12-31vStandaloneDiluted earnings per share (5-year summary)
Net assets per share¥6.62at 2025-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥8.03at 2024-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥187.33at 2023-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥190.57at 2022-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥252.16at 2021-12-31dStandaloneNet assets per share (5-year summary)
Equity ratio58.2%at 2025-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio61.4%at 2024-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio96.1%at 2023-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio83.6%at 2022-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio86.0%at 2021-12-31dStandaloneEquity to asset ratio (5-year summary)
ROE3.0%2023-01-01 → 2023-12-31vStandaloneRate of return on equity (5-year summary)
Shares issued389,026,550at 2025-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued286,377,550at 2024-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued198,470,300at 2023-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued178,623,900at 2022-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued153,072,400at 2021-12-31dStandaloneTotal number of issued shares (5-year summary)
Employees35at 2025-12-31StandaloneNumber of employees
Employees33at 2024-12-31StandaloneNumber of employees
Employees40at 2023-12-31vStandaloneNumber of employees
Employees39at 2022-12-31vStandaloneNumber of employees
Employees42at 2021-12-31dStandaloneNumber of employees

Periods use the dates stated in the filing. d = earlier-year period dated by calendar; v = that date confirmed by the company's own earlier filing.

Segments · 2
SegmentItemPeriodValue
Pharmaceutical Businessreportable segmentemployeesat 2025-12-3156 pure
Pharmaceutical Businessreportable segmentemployeesat 2025-12-3135 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,378
ItemContextValueUnit
Increase decrease in accrued or accrued consumption taxes ope cfCurrentYearDuration38067000JPY
Increase decrease in accounts payable other ope cfPrior1YearDuration-188059000JPY
Increase decrease in accounts payable other ope cfCurrentYearDuration-78836000JPY
Increase decrease in accrued expenses ope cfPrior1YearDuration-7534000JPY
Increase decrease in accrued expenses ope cfCurrentYearDuration471000JPY
Increase decrease in provision for business restructuring ope cfPrior1YearDuration-437598000JPY
Increase decrease in provision for business restructuring ope cfCurrentYearDuration-22443000JPY
Increase decrease in advances received ope cfPrior1YearDuration1950000JPY
Increase decrease in advances received ope cfCurrentYearDuration1950000JPY
Decrease increase in other current assets ope cfPrior1YearDuration47035000JPY
Decrease increase in other current assets ope cfCurrentYearDuration-35077000JPY
Decrease increase in other noncurrent assets ope cfPrior1YearDuration-JPY
Decrease increase in other noncurrent assets ope cfCurrentYearDuration-2588000JPY
Increase decrease in other current liabilities ope cfPrior1YearDuration58101000JPY
Increase decrease in other current liabilities ope cfCurrentYearDuration-24869000JPY
Increase decrease in other noncurrent liabilities ope cfPrior1YearDuration53370000JPY
Increase decrease in other noncurrent liabilities ope cfCurrentYearDuration-107910000JPY
Subtotal ope cfPrior1YearDuration-6594495000JPY
Subtotal ope cfCurrentYearDuration-5744380000JPY
Interest income received ope cfPrior1YearDuration4447000JPY
Interest income received ope cfCurrentYearDuration14626000JPY
Income taxes paid ope cfPrior1YearDuration-22826000JPY
Income taxes paid ope cfCurrentYearDuration-20612000JPY
Net cash provided by used in operating activitiesPrior1YearDuration-6612875000JPY
Net cash provided by used in operating activitiesCurrentYearDuration-5750366000JPY
Payments into restricted cash inv cfPrior1YearDuration-3764000JPY
Payments into restricted cash inv cfCurrentYearDuration-JPY
Proceeds from withdrawal of restricted deposits inv cfPrior1YearDuration-JPY
Proceeds from withdrawal of restricted deposits inv cfCurrentYearDuration1252000JPY
Purchase of property plant and equipment inv cfPrior1YearDuration-67282000JPY
Purchase of property plant and equipment inv cfCurrentYearDuration-14322000JPY
Proceeds from sales of property plant and equipment inv cfPrior1YearDuration-JPY
Proceeds from sales of property plant and equipment inv cfCurrentYearDuration47175000JPY
Purchase of intangible assets inv cfPrior1YearDuration-10170000JPY
Purchase of intangible assets inv cfCurrentYearDuration-JPY
Purchase of investment securities inv cfPrior1YearDuration-56950000JPY
Purchase of investment securities inv cfCurrentYearDuration-JPY
Proceeds from distribution of investment in partnerships inv cfPrior1YearDuration2004000JPY
Proceeds from distribution of investment in partnerships inv cfCurrentYearDuration334000JPY
Payments of long term loans receivable inv cfPrior1YearDuration-JPY
Payments of long term loans receivable inv cfCurrentYearDuration-15000000JPY
Payments for lease and guarantee deposits inv cfPrior1YearDuration-JPY
Payments for lease and guarantee deposits inv cfCurrentYearDuration-625000JPY
Proceeds from collection of lease and guarantee deposits inv cfPrior1YearDuration5360000JPY
Proceeds from collection of lease and guarantee deposits inv cfCurrentYearDuration-JPY
Net cash provided by used in investment activitiesPrior1YearDuration-130801000JPY
Net cash provided by used in investment activitiesCurrentYearDuration18814000JPY
Proceeds from issuance of stock resulting from exercise of subscription rights to shares fin cfPrior1YearDuration3008380000JPY
Proceeds from issuance of stock resulting from exercise of subscription rights to shares fin cfCurrentYearDuration5870208000JPY
Proceeds from exercise of stock option fin cfPrior1YearDuration21000JPY

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 20 of 20 passed
balance sheet identityconsolidated 2024-12-31pass rounding
balance sheet identityconsolidated 2025-12-31pass
balance sheet identitynon_consolidated 2024-12-31pass
balance sheet identitynon_consolidated 2025-12-31pass rounding
dei present pass
period resolution pass
statement vs summary · net assetsconsolidated 2023-12-31pass
statement vs summary · net assetsconsolidated 2024-12-31pass
statement vs summary · net assetsconsolidated 2025-12-31pass
statement vs summary · net assetsnon_consolidated 2023-12-31pass
statement vs summary · net assetsnon_consolidated 2024-12-31pass
statement vs summary · net assetsnon_consolidated 2025-12-31pass
statement vs summary · net income attributable to parentconsolidated 2024-01-01/2024-12-31pass
statement vs summary · net income attributable to parentconsolidated 2025-01-01/2025-12-31pass
statement vs summary · operating cash flowconsolidated 2024-01-01/2024-12-31pass
statement vs summary · operating cash flowconsolidated 2025-01-01/2025-12-31pass
statement vs summary · total assetsconsolidated 2024-12-31pass
statement vs summary · total assetsconsolidated 2025-12-31pass
statement vs summary · total assetsnon_consolidated 2024-12-31pass
statement vs summary · total assetsnon_consolidated 2025-12-31pass