Annual report

Period2022-01-01 → 2022-12-31

Filed2023-03-31

StandardJapan GAAP

ConsolidatedYes

Data checks20 of 20 passed

Key figures · 123

Metric	Value	Period	Scope	Source row
Operating income	−¥16.3bn	2022-01-01 → 2022-12-31	Cons.	Operating income
Operating income	−¥15.6bn	2021-01-01 → 2021-12-31	Cons.	Operating income
Ordinary income	−¥14.6bn	2022-01-01 → 2022-12-31	Cons.	Ordinary income
Ordinary income	−¥13.6bn	2021-01-01 → 2021-12-31	Cons.	Ordinary income
Ordinary income	−¥6.6bn	2020-01-01 → 2020-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Cons.	Ordinary income loss (5-year summary)
Profit before tax	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Income before income taxes
Profit before tax	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Income before income taxes
Net income (owners)	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥4.2bn	2020-01-01 → 2020-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.8bn	2019-01-01 → 2019-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.0bn	2018-01-01 → 2018-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss
Net income	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss
Total assets	¥38.8bn	at 2022-12-31	Cons.	Assets
Total assets	¥45.5bn	at 2021-12-31	Cons.	Assets
Total assets	¥38.4bn	at 2020-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥12.5bn	at 2019-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥8.1bn	at 2018-12-31^d	Cons.	Total assets (5-year summary)
Total liabilities	¥8.4bn	at 2022-12-31	Cons.	Liabilities
Total liabilities	¥6.8bn	at 2021-12-31	Cons.	Liabilities
Net assets / equity	¥30.4bn	at 2022-12-31	Cons.	Net assets
Net assets / equity	¥38.6bn	at 2021-12-31	Cons.	Net assets
Net assets / equity	¥32.7bn	at 2020-12-31^d	Cons.	Net assets
Net assets / equity	¥12.1bn	at 2019-12-31^d	Cons.	Net assets (5-year summary)
Net assets / equity	¥7.7bn	at 2018-12-31^d	Cons.	Net assets (5-year summary)
Cash and deposits	¥11.0bn	at 2022-12-31	Cons.	Cash and deposits
Cash and deposits	¥17.9bn	at 2021-12-31	Cons.	Cash and deposits
Cash & equivalents	¥11.0bn	at 2022-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥17.8bn	at 2021-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥11.5bn	at 2020-12-31^d	Cons.	Cash and cash equivalents
Cash & equivalents	¥10.0bn	at 2019-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Cash & equivalents	¥5.8bn	at 2018-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Operating cash flow	−¥11.2bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥11.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥3.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.5bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Investing cash flow	−¥97m	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥155m	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥7.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥1.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥123m	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Financing cash flow	¥3.6bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥17.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥11.4bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.7bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.3bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
EPS (basic)	¥-94.29	2022-01-01 → 2022-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-92.86	2021-01-01 → 2021-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.33	2020-01-01 → 2020-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.81	2019-01-01 → 2019-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.46	2018-01-01 → 2018-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
Net assets per share	¥169.77	at 2022-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥251.81	at 2021-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥244.53	at 2020-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥111.83	at 2019-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥78.38	at 2018-12-31^d	Cons.	Net assets per share (5-year summary)
Equity ratio	78.1%	at 2022-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2021-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2020-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.5%	at 2019-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.4%	at 2018-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Employees	138	at 2022-12-31	Cons.	Number of employees
Employees	131	at 2021-12-31	Cons.	Number of employees
Employees	90	at 2020-12-31^d	Cons.	Number of employees
Employees	36	at 2019-12-31^d	Cons.	Number of employees
Employees	36	at 2018-12-31^d	Cons.	Number of employees
Operating income	−¥9.7bn	2022-01-01 → 2022-12-31	Standalone	Operating income
Operating income	−¥10.0bn	2021-01-01 → 2021-12-31	Standalone	Operating income
Ordinary income	−¥8.0bn	2022-01-01 → 2022-12-31	Standalone	Ordinary income
Ordinary income	−¥7.9bn	2021-01-01 → 2021-12-31	Standalone	Ordinary income
Ordinary income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Standalone	Ordinary income loss (5-year summary)
Profit before tax	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Income before income taxes
Profit before tax	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Income before income taxes
Net income	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Profit loss
Net income	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Profit loss
Net income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.8bn	2019-01-01 → 2019-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.0bn	2018-01-01 → 2018-12-31^d	Standalone	Net income loss (5-year summary)
Total assets	¥40.7bn	at 2022-12-31	Standalone	Assets
Total assets	¥44.9bn	at 2021-12-31	Standalone	Assets
Total assets	¥34.1bn	at 2020-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥12.4bn	at 2019-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥7.9bn	at 2018-12-31^d	Standalone	Total assets (5-year summary)
Total liabilities	¥6.6bn	at 2022-12-31	Standalone	Liabilities
Total liabilities	¥6.2bn	at 2021-12-31	Standalone	Liabilities
Net assets / equity	¥34.1bn	at 2022-12-31	Standalone	Net assets
Net assets / equity	¥38.7bn	at 2021-12-31	Standalone	Net assets
Net assets / equity	¥29.4bn	at 2020-12-31^d	Standalone	Net assets
Net assets / equity	¥11.9bn	at 2019-12-31^d	Standalone	Net assets (5-year summary)
Net assets / equity	¥7.6bn	at 2018-12-31^d	Standalone	Net assets (5-year summary)
Cash and deposits	¥8.8bn	at 2022-12-31	Standalone	Cash and deposits
Cash and deposits	¥15.9bn	at 2021-12-31	Standalone	Cash and deposits
EPS (basic)	¥-52	2022-01-01 → 2022-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-54.91	2021-01-01 → 2021-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-44.63	2020-01-01 → 2020-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-36.03	2019-01-01 → 2019-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.67	2018-01-01 → 2018-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
Net assets per share	¥190.57	at 2022-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥252.16	at 2021-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥219.55	at 2020-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥110.56	at 2019-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥77.21	at 2018-12-31^d	Standalone	Net assets per share (5-year summary)
Equity ratio	83.6%	at 2022-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	86.0%	at 2021-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	85.6%	at 2020-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.1%	at 2019-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.3%	at 2018-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Shares issued	178,623,900	at 2022-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	153,072,400	at 2021-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	133,059,400	at 2020-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	106,969,561	at 2019-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	97,981,061	at 2018-12-31^d	Standalone	Total number of issued shares (5-year summary)
Employees	39	at 2022-12-31	Standalone	Number of employees
Employees	42	at 2021-12-31	Standalone	Number of employees
Employees	34	at 2020-12-31^d	Standalone	Number of employees
Employees	33	at 2019-12-31^d	Standalone	Number of employees
Employees	33	at 2018-12-31^d	Standalone	Number of employees

Periods use the dates stated in the filing. ^d = earlier-year period dated by calendar; ^v = that date confirmed by the company's own earlier filing.

Segments · 2

Segment	Item	Period	Value
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	138 pure
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	39 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,274

Item	Context	Value	Unit
Average number of temporary workers	Prior2YearInstant_NonConsolidatedMember	5
Average number of temporary workers	Prior1YearInstant_NonConsolidatedMember	7
Average number of temporary workers	CurrentYearInstant_NonConsolidatedMember	9
Total shareholder return	Prior4YearInstant_NonConsolidatedMember	0.586
Total shareholder return	Prior3YearInstant_NonConsolidatedMember	1.032
Total shareholder return	Prior2YearInstant_NonConsolidatedMember	2.011
Total shareholder return	Prior1YearInstant_NonConsolidatedMember	0.620
Total shareholder return	CurrentYearInstant_NonConsolidatedMember	0.197
Total return on share price index	Prior4YearInstant_NonConsolidatedMember	0.659
Total return on share price index	Prior3YearInstant_NonConsolidatedMember	0.728
Total return on share price index	Prior2YearInstant_NonConsolidatedMember	0.971
Total return on share price index	Prior1YearInstant_NonConsolidatedMember	0.802
Total return on share price index	CurrentYearInstant_NonConsolidatedMember	0.593
Number of employees	CurrentYearInstant_jpcrp030000-asr_E05301-000PharmaceuticalBusinessReportableSegmentMember	138
Average number of temporary workers	CurrentYearInstant_jpcrp030000-asr_E05301-000PharmaceuticalBusinessReportableSegmentMember	9
Number of employees	CurrentYearInstant	138
Average number of temporary workers	CurrentYearInstant	9
Number of employees	CurrentYearInstant_NonConsolidatedMember	39
Average number of temporary workers	CurrentYearInstant_NonConsolidatedMember	9
Average age years information about reporting company information about employees	CurrentYearInstant_NonConsolidatedMember	53.9
Average length of service years information about reporting company information about employees	CurrentYearInstant_NonConsolidatedMember	7.9
Average annual salary information about reporting company information about employees	CurrentYearInstant_NonConsolidatedMember	11206398	JPY
Number of employees	CurrentYearInstant_NonConsolidatedMember_jpcrp030000-asr_E05301-000PharmaceuticalBusinessReportableSegmentMember	39
Average number of temporary workers	CurrentYearInstant_NonConsolidatedMember_jpcrp030000-asr_E05301-000PharmaceuticalBusinessReportableSegmentMember	9
Number of employees	CurrentYearInstant_NonConsolidatedMember	39
Average number of temporary workers	CurrentYearInstant_NonConsolidatedMember	9
Research and development expenses research and development activities	CurrentYearDuration	10999000000	JPY
Capital expenditures overview of capital expenditures etc	CurrentYearDuration	69426000	JPY
Number of issued shares as of fiscal year end issued shares total number of shares etc	FilingDateInstant_OrdinaryShareMember	178623900
Number of issued shares as of filing date issued shares total number of shares etc	FilingDateInstant_OrdinaryShareMember	186423900
Number of issued shares as of fiscal year end issued shares total number of shares etc	FilingDateInstant	178623900
Number of issued shares as of filing date issued shares total number of shares etc	FilingDateInstant	186423900
Number of shares constituting one unit	CurrentYearInstant_OrdinaryShareMember	100
Number of shareholders national and local governments	CurrentYearInstant_OrdinaryShareMember	1
Number of shareholders financial institutions	CurrentYearInstant_OrdinaryShareMember	4
Number of shareholders financial service providers	CurrentYearInstant_OrdinaryShareMember	49
Number of shareholders other corporations	CurrentYearInstant_OrdinaryShareMember	666
Number of shareholders foreign investors other than individuals	CurrentYearInstant_OrdinaryShareMember	79
Number of shareholders foreign individual investors	CurrentYearInstant_OrdinaryShareMember	245
Number of shareholders individuals and others	CurrentYearInstant_OrdinaryShareMember	112820
Number of shareholders total	CurrentYearInstant_OrdinaryShareMember	113864
Number of shares held number of units national and local governments	CurrentYearInstant_OrdinaryShareMember	40
Number of shares held number of units financial institutions	CurrentYearInstant_OrdinaryShareMember	8297
Number of shares held number of units financial service providers	CurrentYearInstant_OrdinaryShareMember	108519
Number of shares held number of units other corporations	CurrentYearInstant_OrdinaryShareMember	61672
Number of shares held number of units foreign investors other than individuals	CurrentYearInstant_OrdinaryShareMember	77177
Number of shares held number of units foreign individual investors	CurrentYearInstant_OrdinaryShareMember	3715
Number of shares held number of units individuals and others	CurrentYearInstant_OrdinaryShareMember	1526153
Number of shares held number of units total	CurrentYearInstant_OrdinaryShareMember	1785573
Number of shares held shares less than one unit	CurrentYearInstant_OrdinaryShareMember	66600

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 20 of 20 passed

balance sheet identity	consolidated 2021-12-31	pass
balance sheet identity	consolidated 2022-12-31	pass rounding
balance sheet identity	non_consolidated 2021-12-31	pass rounding
balance sheet identity	non_consolidated 2022-12-31	pass
dei present		pass
period resolution		pass
statement vs summary · net assets	consolidated 2020-12-31	pass
statement vs summary · net assets	consolidated 2021-12-31	pass
statement vs summary · net assets	consolidated 2022-12-31	pass
statement vs summary · net assets	non_consolidated 2020-12-31	pass
statement vs summary · net assets	non_consolidated 2021-12-31	pass
statement vs summary · net assets	non_consolidated 2022-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · operating cash flow	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · operating cash flow	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · total assets	consolidated 2021-12-31	pass
statement vs summary · total assets	consolidated 2022-12-31	pass
statement vs summary · total assets	non_consolidated 2021-12-31	pass
statement vs summary · total assets	non_consolidated 2022-12-31	pass