Annual report

Period2022-01-01 → 2022-12-31

Filed2023-03-31

StandardJapan GAAP

ConsolidatedYes

Data checks20 of 20 passed

Key figures · 123

Metric	Value	Period	Scope	Source row
Operating income	−¥16.3bn	2022-01-01 → 2022-12-31	Cons.	Operating income
Operating income	−¥15.6bn	2021-01-01 → 2021-12-31	Cons.	Operating income
Ordinary income	−¥14.6bn	2022-01-01 → 2022-12-31	Cons.	Ordinary income
Ordinary income	−¥13.6bn	2021-01-01 → 2021-12-31	Cons.	Ordinary income
Ordinary income	−¥6.6bn	2020-01-01 → 2020-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Cons.	Ordinary income loss (5-year summary)
Profit before tax	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Income before income taxes
Profit before tax	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Income before income taxes
Net income (owners)	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥4.2bn	2020-01-01 → 2020-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.8bn	2019-01-01 → 2019-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.0bn	2018-01-01 → 2018-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss
Net income	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss
Total assets	¥38.8bn	at 2022-12-31	Cons.	Assets
Total assets	¥45.5bn	at 2021-12-31	Cons.	Assets
Total assets	¥38.4bn	at 2020-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥12.5bn	at 2019-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥8.1bn	at 2018-12-31^d	Cons.	Total assets (5-year summary)
Total liabilities	¥8.4bn	at 2022-12-31	Cons.	Liabilities
Total liabilities	¥6.8bn	at 2021-12-31	Cons.	Liabilities
Net assets / equity	¥30.4bn	at 2022-12-31	Cons.	Net assets
Net assets / equity	¥38.6bn	at 2021-12-31	Cons.	Net assets
Net assets / equity	¥32.7bn	at 2020-12-31^d	Cons.	Net assets
Net assets / equity	¥12.1bn	at 2019-12-31^d	Cons.	Net assets (5-year summary)
Net assets / equity	¥7.7bn	at 2018-12-31^d	Cons.	Net assets (5-year summary)
Cash and deposits	¥11.0bn	at 2022-12-31	Cons.	Cash and deposits
Cash and deposits	¥17.9bn	at 2021-12-31	Cons.	Cash and deposits
Cash & equivalents	¥11.0bn	at 2022-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥17.8bn	at 2021-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥11.5bn	at 2020-12-31^d	Cons.	Cash and cash equivalents
Cash & equivalents	¥10.0bn	at 2019-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Cash & equivalents	¥5.8bn	at 2018-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Operating cash flow	−¥11.2bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥11.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥3.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.5bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Investing cash flow	−¥97m	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥155m	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥7.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥1.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥123m	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Financing cash flow	¥3.6bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥17.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥11.4bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.7bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.3bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
EPS (basic)	¥-94.29	2022-01-01 → 2022-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-92.86	2021-01-01 → 2021-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.33	2020-01-01 → 2020-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.81	2019-01-01 → 2019-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.46	2018-01-01 → 2018-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
Net assets per share	¥169.77	at 2022-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥251.81	at 2021-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥244.53	at 2020-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥111.83	at 2019-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥78.38	at 2018-12-31^d	Cons.	Net assets per share (5-year summary)
Equity ratio	78.1%	at 2022-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2021-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2020-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.5%	at 2019-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.4%	at 2018-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Employees	138	at 2022-12-31	Cons.	Number of employees
Employees	131	at 2021-12-31	Cons.	Number of employees
Employees	90	at 2020-12-31^d	Cons.	Number of employees
Employees	36	at 2019-12-31^d	Cons.	Number of employees
Employees	36	at 2018-12-31^d	Cons.	Number of employees
Operating income	−¥9.7bn	2022-01-01 → 2022-12-31	Standalone	Operating income
Operating income	−¥10.0bn	2021-01-01 → 2021-12-31	Standalone	Operating income
Ordinary income	−¥8.0bn	2022-01-01 → 2022-12-31	Standalone	Ordinary income
Ordinary income	−¥7.9bn	2021-01-01 → 2021-12-31	Standalone	Ordinary income
Ordinary income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Standalone	Ordinary income loss (5-year summary)
Profit before tax	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Income before income taxes
Profit before tax	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Income before income taxes
Net income	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Profit loss
Net income	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Profit loss
Net income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.8bn	2019-01-01 → 2019-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.0bn	2018-01-01 → 2018-12-31^d	Standalone	Net income loss (5-year summary)
Total assets	¥40.7bn	at 2022-12-31	Standalone	Assets
Total assets	¥44.9bn	at 2021-12-31	Standalone	Assets
Total assets	¥34.1bn	at 2020-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥12.4bn	at 2019-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥7.9bn	at 2018-12-31^d	Standalone	Total assets (5-year summary)
Total liabilities	¥6.6bn	at 2022-12-31	Standalone	Liabilities
Total liabilities	¥6.2bn	at 2021-12-31	Standalone	Liabilities
Net assets / equity	¥34.1bn	at 2022-12-31	Standalone	Net assets
Net assets / equity	¥38.7bn	at 2021-12-31	Standalone	Net assets
Net assets / equity	¥29.4bn	at 2020-12-31^d	Standalone	Net assets
Net assets / equity	¥11.9bn	at 2019-12-31^d	Standalone	Net assets (5-year summary)
Net assets / equity	¥7.6bn	at 2018-12-31^d	Standalone	Net assets (5-year summary)
Cash and deposits	¥8.8bn	at 2022-12-31	Standalone	Cash and deposits
Cash and deposits	¥15.9bn	at 2021-12-31	Standalone	Cash and deposits
EPS (basic)	¥-52	2022-01-01 → 2022-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-54.91	2021-01-01 → 2021-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-44.63	2020-01-01 → 2020-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-36.03	2019-01-01 → 2019-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.67	2018-01-01 → 2018-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
Net assets per share	¥190.57	at 2022-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥252.16	at 2021-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥219.55	at 2020-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥110.56	at 2019-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥77.21	at 2018-12-31^d	Standalone	Net assets per share (5-year summary)
Equity ratio	83.6%	at 2022-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	86.0%	at 2021-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	85.6%	at 2020-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.1%	at 2019-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.3%	at 2018-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Shares issued	178,623,900	at 2022-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	153,072,400	at 2021-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	133,059,400	at 2020-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	106,969,561	at 2019-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	97,981,061	at 2018-12-31^d	Standalone	Total number of issued shares (5-year summary)
Employees	39	at 2022-12-31	Standalone	Number of employees
Employees	42	at 2021-12-31	Standalone	Number of employees
Employees	34	at 2020-12-31^d	Standalone	Number of employees
Employees	33	at 2019-12-31^d	Standalone	Number of employees
Employees	33	at 2018-12-31^d	Standalone	Number of employees

Periods use the dates stated in the filing. ^d = earlier-year period dated by calendar; ^v = that date confirmed by the company's own earlier filing.

Segments · 2

Segment	Item	Period	Value
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	138 pure
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	39 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,274

Item	Context	Value
Address major shareholders	CurrentYearInstant_No3MajorShareholdersMember	Text · Plus
Name major shareholders	CurrentYearInstant_No4MajorShareholdersMember	Original text (Japanese) MLPFS CUSTODY ACCOUNT(常任代理人 BOFA証券株式会社)
Address major shareholders	CurrentYearInstant_No4MajorShareholdersMember	Text · Plus
Name major shareholders	CurrentYearInstant_No5MajorShareholdersMember	Original text (Japanese) 塩野義製薬株式会社
Address major shareholders	CurrentYearInstant_No5MajorShareholdersMember	Original text (Japanese) 大阪府大阪市中央区道修町３－１－８
Name major shareholders	CurrentYearInstant_No6MajorShareholdersMember	Original text (Japanese) 林　勇一郎
Address major shareholders	CurrentYearInstant_No6MajorShareholdersMember	Original text (Japanese) 東京都渋谷区
Name major shareholders	CurrentYearInstant_No7MajorShareholdersMember	Text · Plus
Address major shareholders	CurrentYearInstant_No7MajorShareholdersMember	Text · Plus
Name major shareholders	CurrentYearInstant_No8MajorShareholdersMember	Original text (Japanese) MSIP CLIENT SECURITIES(常任代理人モルガン・スタンレーMUFG証券株式会社)
Address major shareholders	CurrentYearInstant_No8MajorShareholdersMember	Text · Plus
Name major shareholders	CurrentYearInstant_No9MajorShareholdersMember	Original text (Japanese) 河合　裕
Address major shareholders	CurrentYearInstant_No9MajorShareholdersMember	Original text (Japanese) 大阪府堺市堺区
Name major shareholders	CurrentYearInstant_No10MajorShareholdersMember	Original text (Japanese) 森下　竜一
Address major shareholders	CurrentYearInstant_No10MajorShareholdersMember	Original text (Japanese) 大阪府吹田市
Issued shares voting rights (text)	FilingDateInstant	Text · Plus
Description issued shares voting rights	CurrentYearInstant_SharesWithNoVotingRightsMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithRestrictedVotingRightsTreasurySharesEtcMember	－
Description issued shares voting rights	CurrentYearInstant_SharesWithRestrictedVotingRightsOtherMember	－
Description issued shares voting rights	CurrentYearInstant_OrdinarySharesTreasurySharesSharesWithFullVotingRightsTreasurySharesEtcMember	－
Description issued shares voting rights	CurrentYearInstant_OrdinarySharesSharesWithFullVotingRightsOtherMember	－
Description issued shares voting rights	CurrentYearInstant_OrdinarySharesSharesLessThanOneUnitMember	－
Treasury shares etc (text)	FilingDateInstant	Text · Plus
Name of shareholder treasury shares etc	CurrentYearInstant_Row1Member	－
Address of shareholder treasury shares etc	CurrentYearInstant_Row1Member	－
Classes of shares etc (text)	FilingDateInstant	Text · Plus
Acquisitions by resolution of shareholders meeting (text)	FilingDateInstant	Text · Plus
Acquisitions by resolution of board of directors meeting (text)	FilingDateInstant	Text · Plus
Acquisitions not based on resolution of shareholders meeting or board of directors meeting (text)	FilingDateInstant	Text · Plus
Disposals or holding of acquired treasury shares (text)	FilingDateInstant	Text · Plus
Dividend policy (text)	FilingDateInstant	Text · Plus
Overview of corporate governance (text)	FilingDateInstant	Text · Plus
Corporate governance company with corporate auditors (text)	FilingDateInstant	Text · Plus
Information about officers (text)	FilingDateInstant	Text · Plus
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000YamadaEiMember	Original text (Japanese) 代表取締役社長執行役員
Name information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000YamadaEiMember	Original text (Japanese) 山田英
Date of birth information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000YamadaEiMember	1950-06-27
Career summary information about directors and corporate auditors (text)	FilingDateInstant_jpcrp030000-asr_E05301-000YamadaEiMember	Text · Plus
Term of office information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000YamadaEiMember	Original text (Japanese) 注１
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000SatoNaoyaMember	Original text (Japanese) 取締役
Name information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000SatoNaoyaMember	Original text (Japanese) 佐藤　尚哉
Date of birth information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000SatoNaoyaMember	1960-04-25
Career summary information about directors and corporate auditors (text)	FilingDateInstant_jpcrp030000-asr_E05301-000SatoNaoyaMember	Text · Plus
Term of office information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000SatoNaoyaMember	Original text (Japanese) 注１
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000EikiNorikazuMember	Original text (Japanese) 取締役
Name information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000EikiNorikazuMember	Original text (Japanese) 栄木憲和
Date of birth information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000EikiNorikazuMember	1948-04-17
Career summary information about directors and corporate auditors (text)	FilingDateInstant_jpcrp030000-asr_E05301-000EikiNorikazuMember	Text · Plus
Term of office information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000EikiNorikazuMember	Original text (Japanese) 注１
Official title or position information about directors and corporate auditors	FilingDateInstant_jpcrp030000-asr_E05301-000KomamuraJunichiMember	Original text (Japanese) 取締役

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 20 of 20 passed

balance sheet identity	consolidated 2021-12-31	pass
balance sheet identity	consolidated 2022-12-31	pass rounding
balance sheet identity	non_consolidated 2021-12-31	pass rounding
balance sheet identity	non_consolidated 2022-12-31	pass
dei present		pass
period resolution		pass
statement vs summary · net assets	consolidated 2020-12-31	pass
statement vs summary · net assets	consolidated 2021-12-31	pass
statement vs summary · net assets	consolidated 2022-12-31	pass
statement vs summary · net assets	non_consolidated 2020-12-31	pass
statement vs summary · net assets	non_consolidated 2021-12-31	pass
statement vs summary · net assets	non_consolidated 2022-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · operating cash flow	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · operating cash flow	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · total assets	consolidated 2021-12-31	pass
statement vs summary · total assets	consolidated 2022-12-31	pass
statement vs summary · total assets	non_consolidated 2021-12-31	pass
statement vs summary · total assets	non_consolidated 2022-12-31	pass