Annual report

Period2022-01-01 → 2022-12-31

Filed2023-03-31

StandardJapan GAAP

ConsolidatedYes

Data checks20 of 20 passed

Key figures · 123

Metric	Value	Period	Scope	Source row
Operating income	−¥16.3bn	2022-01-01 → 2022-12-31	Cons.	Operating income
Operating income	−¥15.6bn	2021-01-01 → 2021-12-31	Cons.	Operating income
Ordinary income	−¥14.6bn	2022-01-01 → 2022-12-31	Cons.	Ordinary income
Ordinary income	−¥13.6bn	2021-01-01 → 2021-12-31	Cons.	Ordinary income
Ordinary income	−¥6.6bn	2020-01-01 → 2020-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Cons.	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Cons.	Ordinary income loss (5-year summary)
Profit before tax	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Income before income taxes
Profit before tax	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Income before income taxes
Net income (owners)	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss attributable to owners of parent
Net income (owners)	−¥4.2bn	2020-01-01 → 2020-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.8bn	2019-01-01 → 2019-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income (owners)	−¥3.0bn	2018-01-01 → 2018-12-31^d	Cons.	Profit loss attributable to owners of parent (5-year summary)
Net income	−¥14.7bn	2022-01-01 → 2022-12-31	Cons.	Profit loss
Net income	−¥13.7bn	2021-01-01 → 2021-12-31	Cons.	Profit loss
Total assets	¥38.8bn	at 2022-12-31	Cons.	Assets
Total assets	¥45.5bn	at 2021-12-31	Cons.	Assets
Total assets	¥38.4bn	at 2020-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥12.5bn	at 2019-12-31^d	Cons.	Total assets (5-year summary)
Total assets	¥8.1bn	at 2018-12-31^d	Cons.	Total assets (5-year summary)
Total liabilities	¥8.4bn	at 2022-12-31	Cons.	Liabilities
Total liabilities	¥6.8bn	at 2021-12-31	Cons.	Liabilities
Net assets / equity	¥30.4bn	at 2022-12-31	Cons.	Net assets
Net assets / equity	¥38.6bn	at 2021-12-31	Cons.	Net assets
Net assets / equity	¥32.7bn	at 2020-12-31^d	Cons.	Net assets
Net assets / equity	¥12.1bn	at 2019-12-31^d	Cons.	Net assets (5-year summary)
Net assets / equity	¥7.7bn	at 2018-12-31^d	Cons.	Net assets (5-year summary)
Cash and deposits	¥11.0bn	at 2022-12-31	Cons.	Cash and deposits
Cash and deposits	¥17.9bn	at 2021-12-31	Cons.	Cash and deposits
Cash & equivalents	¥11.0bn	at 2022-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥17.8bn	at 2021-12-31	Cons.	Cash and cash equivalents
Cash & equivalents	¥11.5bn	at 2020-12-31^d	Cons.	Cash and cash equivalents
Cash & equivalents	¥10.0bn	at 2019-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Cash & equivalents	¥5.8bn	at 2018-12-31^d	Cons.	Cash and cash equivalents (5-year summary)
Operating cash flow	−¥11.2bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥11.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in operating activities
Operating cash flow	−¥3.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Operating cash flow	−¥2.5bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in operating activities (5-year summary)
Investing cash flow	−¥97m	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥155m	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in investment activities
Investing cash flow	−¥7.0bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥1.2bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Investing cash flow	−¥123m	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in investing activities (5-year summary)
Financing cash flow	¥3.6bn	2022-01-01 → 2022-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥17.4bn	2021-01-01 → 2021-12-31	Cons.	Net cash provided by used in financing activities
Financing cash flow	¥11.4bn	2020-01-01 → 2020-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.7bn	2019-01-01 → 2019-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
Financing cash flow	¥7.3bn	2018-01-01 → 2018-12-31^d	Cons.	Net cash provided by used in financing activities (5-year summary)
EPS (basic)	¥-94.29	2022-01-01 → 2022-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-92.86	2021-01-01 → 2021-12-31	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.33	2020-01-01 → 2020-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-35.81	2019-01-01 → 2019-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.46	2018-01-01 → 2018-12-31^d	Cons.	Basic earnings loss per share (5-year summary)
Net assets per share	¥169.77	at 2022-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥251.81	at 2021-12-31	Cons.	Net assets per share (5-year summary)
Net assets per share	¥244.53	at 2020-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥111.83	at 2019-12-31^d	Cons.	Net assets per share (5-year summary)
Net assets per share	¥78.38	at 2018-12-31^d	Cons.	Net assets per share (5-year summary)
Equity ratio	78.1%	at 2022-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2021-12-31	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	84.8%	at 2020-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.5%	at 2019-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Equity ratio	95.4%	at 2018-12-31^d	Cons.	Equity to asset ratio (5-year summary)
Employees	138	at 2022-12-31	Cons.	Number of employees
Employees	131	at 2021-12-31	Cons.	Number of employees
Employees	90	at 2020-12-31^d	Cons.	Number of employees
Employees	36	at 2019-12-31^d	Cons.	Number of employees
Employees	36	at 2018-12-31^d	Cons.	Number of employees
Operating income	−¥9.7bn	2022-01-01 → 2022-12-31	Standalone	Operating income
Operating income	−¥10.0bn	2021-01-01 → 2021-12-31	Standalone	Operating income
Ordinary income	−¥8.0bn	2022-01-01 → 2022-12-31	Standalone	Ordinary income
Ordinary income	−¥7.9bn	2021-01-01 → 2021-12-31	Standalone	Ordinary income
Ordinary income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.3bn	2019-01-01 → 2019-12-31^d	Standalone	Ordinary income loss (5-year summary)
Ordinary income	−¥3.1bn	2018-01-01 → 2018-12-31^d	Standalone	Ordinary income loss (5-year summary)
Profit before tax	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Income before income taxes
Profit before tax	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Income before income taxes
Net income	−¥8.1bn	2022-01-01 → 2022-12-31	Standalone	Profit loss
Net income	−¥8.1bn	2021-01-01 → 2021-12-31	Standalone	Profit loss
Net income	−¥5.3bn	2020-01-01 → 2020-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.8bn	2019-01-01 → 2019-12-31^d	Standalone	Net income loss (5-year summary)
Net income	−¥3.0bn	2018-01-01 → 2018-12-31^d	Standalone	Net income loss (5-year summary)
Total assets	¥40.7bn	at 2022-12-31	Standalone	Assets
Total assets	¥44.9bn	at 2021-12-31	Standalone	Assets
Total assets	¥34.1bn	at 2020-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥12.4bn	at 2019-12-31^d	Standalone	Total assets (5-year summary)
Total assets	¥7.9bn	at 2018-12-31^d	Standalone	Total assets (5-year summary)
Total liabilities	¥6.6bn	at 2022-12-31	Standalone	Liabilities
Total liabilities	¥6.2bn	at 2021-12-31	Standalone	Liabilities
Net assets / equity	¥34.1bn	at 2022-12-31	Standalone	Net assets
Net assets / equity	¥38.7bn	at 2021-12-31	Standalone	Net assets
Net assets / equity	¥29.4bn	at 2020-12-31^d	Standalone	Net assets
Net assets / equity	¥11.9bn	at 2019-12-31^d	Standalone	Net assets (5-year summary)
Net assets / equity	¥7.6bn	at 2018-12-31^d	Standalone	Net assets (5-year summary)
Cash and deposits	¥8.8bn	at 2022-12-31	Standalone	Cash and deposits
Cash and deposits	¥15.9bn	at 2021-12-31	Standalone	Cash and deposits
EPS (basic)	¥-52	2022-01-01 → 2022-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-54.91	2021-01-01 → 2021-12-31	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-44.63	2020-01-01 → 2020-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-36.03	2019-01-01 → 2019-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
EPS (basic)	¥-34.67	2018-01-01 → 2018-12-31^d	Standalone	Basic earnings loss per share (5-year summary)
Net assets per share	¥190.57	at 2022-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥252.16	at 2021-12-31	Standalone	Net assets per share (5-year summary)
Net assets per share	¥219.55	at 2020-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥110.56	at 2019-12-31^d	Standalone	Net assets per share (5-year summary)
Net assets per share	¥77.21	at 2018-12-31^d	Standalone	Net assets per share (5-year summary)
Equity ratio	83.6%	at 2022-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	86.0%	at 2021-12-31	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	85.6%	at 2020-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.1%	at 2019-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Equity ratio	95.3%	at 2018-12-31^d	Standalone	Equity to asset ratio (5-year summary)
Shares issued	178,623,900	at 2022-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	153,072,400	at 2021-12-31	Standalone	Total number of issued shares (5-year summary)
Shares issued	133,059,400	at 2020-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	106,969,561	at 2019-12-31^d	Standalone	Total number of issued shares (5-year summary)
Shares issued	97,981,061	at 2018-12-31^d	Standalone	Total number of issued shares (5-year summary)
Employees	39	at 2022-12-31	Standalone	Number of employees
Employees	42	at 2021-12-31	Standalone	Number of employees
Employees	34	at 2020-12-31^d	Standalone	Number of employees
Employees	33	at 2019-12-31^d	Standalone	Number of employees
Employees	33	at 2018-12-31^d	Standalone	Number of employees

Periods use the dates stated in the filing. ^d = earlier-year period dated by calendar; ^v = that date confirmed by the company's own earlier filing.

Segments · 2

Segment	Item	Period	Value
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	138 pure
Pharmaceutical Businessreportable segment	employees	at 2022-12-31	39 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,274

Item	Context	Value	Unit
Valuation difference on available for sale securities	CurrentYearInstant	19396000	JPY
Foreign currency translation adjustment	Prior1YearInstant	1904012000	JPY
Foreign currency translation adjustment	CurrentYearInstant	4841242000	JPY
Valuation and translation adjustments	Prior1YearInstant	1940453000	JPY
Valuation and translation adjustments	CurrentYearInstant	4860639000	JPY
Subscription rights to shares	Prior1YearInstant	89332000	JPY
Subscription rights to shares	CurrentYearInstant	100984000	JPY
Net assets	Prior1YearInstant	38634741000	JPY
Net assets	CurrentYearInstant	30425406000	JPY
Liabilities and net assets	Prior1YearInstant	45455746000	JPY
Liabilities and net assets	CurrentYearInstant	38820711000	JPY
Net sales of finished goods rev oa	Prior1YearDuration	34669000	JPY
Net sales of finished goods rev oa	CurrentYearDuration	11614000	JPY
Commission income rev oa	Prior1YearDuration	29478000	JPY
Commission income rev oa	CurrentYearDuration	55446000	JPY
Business revenues	Prior1YearDuration	64148000	JPY
Business revenues	CurrentYearDuration	67061000	JPY
Cost of sales	Prior1YearDuration	56721000	JPY
Cost of sales	CurrentYearDuration	93889000	JPY
Research and development expenses sga	Prior1YearDuration	10783813000	JPY
Research and development expenses sga	CurrentYearDuration	10999325000	JPY
Selling general and administrative expenses	Prior1YearDuration	4855698000	JPY
Selling general and administrative expenses	CurrentYearDuration	5290649000	JPY
Business expenses	Prior1YearDuration	15696233000	JPY
Business expenses	CurrentYearDuration	16383864000	JPY
Operating income	Prior1YearDuration	-15632085000	JPY
Operating income	CurrentYearDuration	-16316803000	JPY
Interest income noi	Prior1YearDuration	566000	JPY
Interest income noi	CurrentYearDuration	1830000	JPY
Foreign exchange gains noi	Prior1YearDuration	599611000	JPY
Foreign exchange gains noi	CurrentYearDuration	1322156000	JPY
Subsidy income noi	Prior1YearDuration	1500850000	JPY
Subsidy income noi	CurrentYearDuration	393514000	JPY
Commission fee noi	Prior1YearDuration	13212000	JPY
Commission fee noi	CurrentYearDuration	9768000	JPY
Gain on investments in partnership noi	Prior1YearDuration	26343000	JPY
Gain on investments in partnership noi	CurrentYearDuration	－	JPY
Miscellaneous income noi	Prior1YearDuration	466000	JPY
Miscellaneous income noi	CurrentYearDuration	6235000	JPY
Non operating income	Prior1YearDuration	2141051000	JPY
Non operating income	CurrentYearDuration	1733506000	JPY
Stock issuance cost noe	Prior1YearDuration	96141000	JPY
Stock issuance cost noe	CurrentYearDuration	24949000	JPY
Loss on investments in partnership noe	Prior1YearDuration	－	JPY
Loss on investments in partnership noe	CurrentYearDuration	806000	JPY
Share acquisition rights issuance costs noe	Prior1YearDuration	1798000	JPY
Share acquisition rights issuance costs noe	CurrentYearDuration	962000	JPY
Non operating expenses	Prior1YearDuration	97939000	JPY
Non operating expenses	CurrentYearDuration	26718000	JPY
Ordinary income	Prior1YearDuration	-13588973000	JPY

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 20 of 20 passed

balance sheet identity	consolidated 2021-12-31	pass
balance sheet identity	consolidated 2022-12-31	pass rounding
balance sheet identity	non_consolidated 2021-12-31	pass rounding
balance sheet identity	non_consolidated 2022-12-31	pass
dei present		pass
period resolution		pass
statement vs summary · net assets	consolidated 2020-12-31	pass
statement vs summary · net assets	consolidated 2021-12-31	pass
statement vs summary · net assets	consolidated 2022-12-31	pass
statement vs summary · net assets	non_consolidated 2020-12-31	pass
statement vs summary · net assets	non_consolidated 2021-12-31	pass
statement vs summary · net assets	non_consolidated 2022-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · net income attributable to parent	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · operating cash flow	consolidated 2021-01-01/2021-12-31	pass
statement vs summary · operating cash flow	consolidated 2022-01-01/2022-12-31	pass
statement vs summary · total assets	consolidated 2021-12-31	pass
statement vs summary · total assets	consolidated 2022-12-31	pass
statement vs summary · total assets	non_consolidated 2021-12-31	pass
statement vs summary · total assets	non_consolidated 2022-12-31	pass