Annual report

Period2025-01-01 → 2025-12-31
Filed2026-03-10
StandardIFRS
ConsolidatedYes
Data checks21 of 21 passed
Key figures · 155
MetricValuePeriodScopeSource row
Revenue¥496.8bn2025-01-01 → 2025-12-31Cons.Revenue IFRS
Revenue¥495.6bn2024-01-01 → 2024-12-31Cons.Revenue IFRS
Revenue¥442.2bn2023-01-01 → 2023-12-31vCons.Revenue IFRS (5-year summary)
Revenue¥398.4bn2022-01-01 → 2022-12-31vCons.Revenue IFRS (5-year summary)
Revenue¥352.2bn2021-01-01 → 2021-12-31dCons.Revenue IFRS (5-year summary)
Profit before tax¥87.2bn2025-01-01 → 2025-12-31Cons.Profit loss before tax IFRS
Profit before tax¥83.5bn2024-01-01 → 2024-12-31Cons.Profit loss before tax IFRS
Profit before tax¥97.2bn2023-01-01 → 2023-12-31vCons.Profit loss before tax IFRS (5-year summary)
Profit before tax¥67.6bn2022-01-01 → 2022-12-31vCons.Profit loss before tax IFRS (5-year summary)
Profit before tax¥60.0bn2021-01-01 → 2021-12-31dCons.Profit loss before tax IFRS (5-year summary)
Net income (owners)¥67.0bn2025-01-01 → 2025-12-31Cons.Profit loss attributable to owners of parent IFRS
Net income (owners)¥59.9bn2024-01-01 → 2024-12-31Cons.Profit loss attributable to owners of parent IFRS
Net income (owners)¥81.2bn2023-01-01 → 2023-12-31vCons.Profit loss attributable to owners of parent IFRS (5-year summary)
Net income (owners)¥53.6bn2022-01-01 → 2022-12-31vCons.Profit loss attributable to owners of parent IFRS (5-year summary)
Net income (owners)¥52.3bn2021-01-01 → 2021-12-31dCons.Profit loss attributable to owners of parent IFRS (5-year summary)
Net income¥67.0bn2025-01-01 → 2025-12-31Cons.Profit loss IFRS
Net income¥59.9bn2024-01-01 → 2024-12-31Cons.Profit loss IFRS
Total assets¥1.11Tat 2025-12-31Cons.Assets IFRS
Total assets¥1.07Tat 2024-12-31Cons.Assets IFRS
Total assets¥1.03Tat 2023-12-31vCons.Total assets IFRS (5-year summary)
Total assets¥939.9bnat 2022-12-31vCons.Total assets IFRS (5-year summary)
Total assets¥921.9bnat 2021-12-31dCons.Total assets IFRS (5-year summary)
Total liabilities¥214.5bnat 2025-12-31Cons.Liabilities IFRS
Total liabilities¥216.6bnat 2024-12-31Cons.Liabilities IFRS
Net assets / equity¥893.3bnat 2025-12-31Cons.Equity IFRS
Net assets / equity¥850.8bnat 2024-12-31Cons.Equity IFRS
Net assets / equity¥836.4bnat 2023-12-31vCons.Equity IFRS
Equity (owners)¥893.3bnat 2025-12-31Cons.Equity attributable to owners of parent IFRS
Equity (owners)¥850.8bnat 2024-12-31Cons.Equity attributable to owners of parent IFRS
Equity (owners)¥836.4bnat 2023-12-31vCons.Equity attributable to owners of parent IFRS (5-year summary)
Equity (owners)¥762.8bnat 2022-12-31vCons.Equity attributable to owners of parent IFRS (5-year summary)
Equity (owners)¥737.2bnat 2021-12-31dCons.Equity attributable to owners of parent IFRS (5-year summary)
Cash & equivalents¥218.8bnat 2025-12-31Cons.Cash and cash equivalents IFRS
Cash & equivalents¥244.7bnat 2024-12-31Cons.Cash and cash equivalents IFRS
Cash & equivalents¥403.1bnat 2023-12-31vCons.Cash and cash equivalents IFRS
Cash & equivalents¥339.2bnat 2022-12-31vCons.Cash and cash equivalents IFRS (5-year summary)
Cash & equivalents¥335.1bnat 2021-12-31dCons.Cash and cash equivalents IFRS (5-year summary)
Operating cash flow¥96.6bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in operating activities IFRS
Operating cash flow¥67.9bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in operating activities IFRS
Operating cash flow¥115.6bn2023-01-01 → 2023-12-31vCons.Cash flows from used in operating activities IFRS (5-year summary)
Operating cash flow¥48.7bn2022-01-01 → 2022-12-31vCons.Cash flows from used in operating activities IFRS (5-year summary)
Operating cash flow¥86.5bn2021-01-01 → 2021-12-31dCons.Cash flows from used in operating activities IFRS (5-year summary)
Investing cash flow−¥89.2bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in investing activities IFRS
Investing cash flow−¥142.4bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in investing activities IFRS
Investing cash flow−¥20.4bn2023-01-01 → 2023-12-31vCons.Cash flows from used in investing activities IFRS (5-year summary)
Investing cash flow−¥17.2bn2022-01-01 → 2022-12-31vCons.Cash flows from used in investing activities IFRS (5-year summary)
Investing cash flow−¥11.4bn2021-01-01 → 2021-12-31dCons.Cash flows from used in investing activities IFRS (5-year summary)
Financing cash flow−¥36.9bn2025-01-01 → 2025-12-31Cons.Net cash provided by used in financing activities IFRS
Financing cash flow−¥84.7bn2024-01-01 → 2024-12-31Cons.Net cash provided by used in financing activities IFRS
Financing cash flow−¥32.5bn2023-01-01 → 2023-12-31vCons.Cash flows from used in financing activities IFRS (5-year summary)
Financing cash flow−¥29.0bn2022-01-01 → 2022-12-31vCons.Cash flows from used in financing activities IFRS (5-year summary)
Financing cash flow−¥28.4bn2021-01-01 → 2021-12-31dCons.Cash flows from used in financing activities IFRS (5-year summary)
EPS (basic)¥128.072025-01-01 → 2025-12-31Cons.Basic earnings loss per share IFRS
EPS (basic)¥113.062024-01-01 → 2024-12-31Cons.Basic earnings loss per share IFRS
EPS (basic)¥151.032023-01-01 → 2023-12-31vCons.Basic earnings loss per share IFRS (5-year summary)
EPS (basic)¥99.682022-01-01 → 2022-12-31vCons.Basic earnings loss per share IFRS (5-year summary)
EPS (basic)¥97.432021-01-01 → 2021-12-31dCons.Basic earnings loss per share IFRS (5-year summary)
EPS (diluted)¥128.072025-01-01 → 2025-12-31Cons.Diluted earnings loss per share IFRS
EPS (diluted)¥113.062024-01-01 → 2024-12-31Cons.Diluted earnings loss per share IFRS
EPS (diluted)¥151.012023-01-01 → 2023-12-31vCons.Diluted earnings loss per share IFRS (5-year summary)
EPS (diluted)¥99.662022-01-01 → 2022-12-31vCons.Diluted earnings loss per share IFRS (5-year summary)
EPS (diluted)¥97.392021-01-01 → 2021-12-31dCons.Diluted earnings loss per share IFRS (5-year summary)
Net assets per share¥1,706.5at 2025-12-31Cons.Equity to asset ratio IFRS (5-year summary)
Net assets per share¥1,625.68at 2024-12-31Cons.Equity to asset ratio IFRS (5-year summary)
Net assets per share¥1,555.81at 2023-12-31vCons.Equity to asset ratio IFRS (5-year summary)
Net assets per share¥1,419.27at 2022-12-31vCons.Equity to asset ratio IFRS (5-year summary)
Net assets per share¥1,371.9at 2021-12-31dCons.Equity to asset ratio IFRS (5-year summary)
Equity ratio80.6%at 2025-12-31Cons.Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio79.7%at 2024-12-31Cons.Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio81.5%at 2023-12-31vCons.Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio81.2%at 2022-12-31vCons.Ratio of owners equity to gross assets IFRS (5-year summary)
Equity ratio80.0%at 2021-12-31dCons.Ratio of owners equity to gross assets IFRS (5-year summary)
ROE7.7%2025-01-01 → 2025-12-31Cons.Rate of return on equity IFRS (5-year summary)
ROE7.1%2024-01-01 → 2024-12-31Cons.Rate of return on equity IFRS (5-year summary)
ROE10.2%2023-01-01 → 2023-12-31vCons.Rate of return on equity IFRS (5-year summary)
ROE7.1%2022-01-01 → 2022-12-31vCons.Rate of return on equity IFRS (5-year summary)
ROE7.3%2021-01-01 → 2021-12-31dCons.Rate of return on equity IFRS (5-year summary)
Employees5,161at 2025-12-31Cons.Number of employees
Employees5,669at 2024-12-31Cons.Number of employees
Employees5,974at 2023-12-31vCons.Number of employees
Employees5,982at 2022-12-31vCons.Number of employees
Employees5,752at 2021-12-31dCons.Number of employees
Revenue¥297.3bn2025-01-01 → 2025-12-31StandaloneNet sales
Revenue¥286.5bn2024-01-01 → 2024-12-31StandaloneNet sales
Revenue¥277.2bn2023-01-01 → 2023-12-31vStandaloneNet sales (5-year summary)
Revenue¥253.8bn2022-01-01 → 2022-12-31vStandaloneNet sales (5-year summary)
Revenue¥237.6bn2021-01-01 → 2021-12-31dStandaloneNet sales (5-year summary)
Operating income¥60.0bn2025-01-01 → 2025-12-31StandaloneOperating income
Operating income−¥4.6bn2024-01-01 → 2024-12-31StandaloneOperating income
Ordinary income¥56.9bn2025-01-01 → 2025-12-31StandaloneOrdinary income
Ordinary income¥68.6bn2024-01-01 → 2024-12-31StandaloneOrdinary income
Ordinary income¥67.2bn2023-01-01 → 2023-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥37.3bn2022-01-01 → 2022-12-31vStandaloneOrdinary income loss (5-year summary)
Ordinary income¥35.2bn2021-01-01 → 2021-12-31dStandaloneOrdinary income loss (5-year summary)
Profit before tax¥42.3bn2025-01-01 → 2025-12-31StandaloneIncome before income taxes
Profit before tax¥54.4bn2024-01-01 → 2024-12-31StandaloneIncome before income taxes
Net income¥32.4bn2025-01-01 → 2025-12-31StandaloneProfit loss
Net income¥60.7bn2024-01-01 → 2024-12-31StandaloneProfit loss
Net income¥50.4bn2023-01-01 → 2023-12-31vStandaloneNet income loss (5-year summary)
Net income¥31.0bn2022-01-01 → 2022-12-31vStandaloneNet income loss (5-year summary)
Net income¥66.4bn2021-01-01 → 2021-12-31dStandaloneNet income loss (5-year summary)
Total assets¥808.5bnat 2025-12-31StandaloneAssets
Total assets¥797.9bnat 2024-12-31StandaloneAssets
Total assets¥869.6bnat 2023-12-31vStandaloneTotal assets (5-year summary)
Total assets¥806.1bnat 2022-12-31vStandaloneTotal assets (5-year summary)
Total assets¥794.1bnat 2021-12-31dStandaloneTotal assets (5-year summary)
Total liabilities¥193.6bnat 2025-12-31StandaloneLiabilities
Total liabilities¥184.9bnat 2024-12-31StandaloneLiabilities
Net assets / equity¥614.9bnat 2025-12-31StandaloneNet assets
Net assets / equity¥613.0bnat 2024-12-31StandaloneNet assets
Net assets / equity¥622.7bnat 2023-12-31vStandaloneNet assets
Net assets / equity¥601.9bnat 2022-12-31vStandaloneNet assets (5-year summary)
Net assets / equity¥596.9bnat 2021-12-31dStandaloneNet assets (5-year summary)
Cash and deposits¥7.9bnat 2025-12-31StandaloneCash and deposits
Cash and deposits¥15.7bnat 2024-12-31StandaloneCash and deposits
EPS (basic)¥61.972025-01-01 → 2025-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥114.572024-01-01 → 2024-12-31StandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥93.72023-01-01 → 2023-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥57.772022-01-01 → 2022-12-31vStandaloneBasic earnings loss per share (5-year summary)
EPS (basic)¥123.522021-01-01 → 2021-12-31dStandaloneBasic earnings loss per share (5-year summary)
EPS (diluted)¥61.972025-01-01 → 2025-12-31StandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥114.572024-01-01 → 2024-12-31StandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥93.692023-01-01 → 2023-12-31vStandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥57.752022-01-01 → 2022-12-31vStandaloneDiluted earnings per share (5-year summary)
EPS (diluted)¥123.472021-01-01 → 2021-12-31dStandaloneDiluted earnings per share (5-year summary)
Dividend per share¥622025-01-01 → 2025-12-31StandaloneDividend paid per share (5-year summary)
Dividend per share¥582024-01-01 → 2024-12-31StandaloneDividend paid per share (5-year summary)
Dividend per share¥562023-01-01 → 2023-12-31vStandaloneDividend paid per share (5-year summary)
Dividend per share¥512022-01-01 → 2022-12-31vStandaloneDividend paid per share (5-year summary)
Dividend per share¥462021-01-01 → 2021-12-31dStandaloneDividend paid per share (5-year summary)
Net assets per share¥1,174.53at 2025-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥1,171.3at 2024-12-31StandaloneNet assets per share (5-year summary)
Net assets per share¥1,158.1at 2023-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥1,119.48at 2022-12-31vStandaloneNet assets per share (5-year summary)
Net assets per share¥1,110.13at 2021-12-31dStandaloneNet assets per share (5-year summary)
Equity ratio76.1%at 2025-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio76.8%at 2024-12-31StandaloneEquity to asset ratio (5-year summary)
Equity ratio71.6%at 2023-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio74.6%at 2022-12-31vStandaloneEquity to asset ratio (5-year summary)
Equity ratio75.1%at 2021-12-31dStandaloneEquity to asset ratio (5-year summary)
ROE5.3%2025-01-01 → 2025-12-31StandaloneRate of return on equity (5-year summary)
ROE9.8%2024-01-01 → 2024-12-31StandaloneRate of return on equity (5-year summary)
ROE8.2%2023-01-01 → 2023-12-31vStandaloneRate of return on equity (5-year summary)
ROE5.2%2022-01-01 → 2022-12-31vStandaloneRate of return on equity (5-year summary)
ROE11.1%2021-01-01 → 2021-12-31dStandaloneRate of return on equity (5-year summary)
Shares issued525,634,500at 2025-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued525,634,500at 2024-12-31StandaloneTotal number of issued shares (5-year summary)
Shares issued540,000,000at 2023-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued540,000,000at 2022-12-31vStandaloneTotal number of issued shares (5-year summary)
Shares issued540,000,000at 2021-12-31dStandaloneTotal number of issued shares (5-year summary)
Employees3,503at 2025-12-31StandaloneNumber of employees
Employees4,013at 2024-12-31StandaloneNumber of employees
Employees4,082at 2023-12-31vStandaloneNumber of employees
Employees4,002at 2022-12-31vStandaloneNumber of employees
Employees3,857at 2021-12-31dStandaloneNumber of employees

Periods use the dates stated in the filing. d = earlier-year period dated by calendar; v = that date confirmed by the company's own earlier filing.

Segments · 2
SegmentItemPeriodValue
Pharmaceuticalsreportable segmentemployeesat 2025-12-315161 pure
Pharmaceuticalsreportable segmentemployeesat 2025-12-313503 pure

Segment names come from EDINET member IDs; not yet mapped to a common taxonomy.

All source rows · 1,910
ItemContextValueUnit
Equity attributable to owners of parent IFRS (5-year summary)Prior3YearInstant762826000000JPY
Equity attributable to owners of parent IFRS (5-year summary)Prior2YearInstant836418000000JPY
Equity attributable to owners of parent IFRS (5-year summary)Prior1YearInstant850811000000JPY
Equity attributable to owners of parent IFRS (5-year summary)CurrentYearInstant893332000000JPY
Total assets IFRS (5-year summary)Prior4YearInstant921872000000JPY
Total assets IFRS (5-year summary)Prior3YearInstant939881000000JPY
Total assets IFRS (5-year summary)Prior2YearInstant1025942000000JPY
Total assets IFRS (5-year summary)Prior1YearInstant1067363000000JPY
Total assets IFRS (5-year summary)CurrentYearInstant1107860000000JPY
Equity to asset ratio IFRS (5-year summary)Prior4YearInstant1371.90
Equity to asset ratio IFRS (5-year summary)Prior3YearInstant1419.27
Equity to asset ratio IFRS (5-year summary)Prior2YearInstant1555.81
Equity to asset ratio IFRS (5-year summary)Prior1YearInstant1625.68
Equity to asset ratio IFRS (5-year summary)CurrentYearInstant1706.50
Basic earnings loss per share IFRS (5-year summary)Prior4YearDuration97.43
Basic earnings loss per share IFRS (5-year summary)Prior3YearDuration99.68
Basic earnings loss per share IFRS (5-year summary)Prior2YearDuration151.03
Basic earnings loss per share IFRS (5-year summary)Prior1YearDuration113.06
Basic earnings loss per share IFRS (5-year summary)CurrentYearDuration128.07
Diluted earnings loss per share IFRS (5-year summary)Prior4YearDuration97.39
Diluted earnings loss per share IFRS (5-year summary)Prior3YearDuration99.66
Diluted earnings loss per share IFRS (5-year summary)Prior2YearDuration151.01
Diluted earnings loss per share IFRS (5-year summary)Prior1YearDuration113.06
Diluted earnings loss per share IFRS (5-year summary)CurrentYearDuration128.07
Ratio of owners equity to gross assets IFRS (5-year summary)Prior4YearInstant0.800
Ratio of owners equity to gross assets IFRS (5-year summary)Prior3YearInstant0.812
Ratio of owners equity to gross assets IFRS (5-year summary)Prior2YearInstant0.815
Ratio of owners equity to gross assets IFRS (5-year summary)Prior1YearInstant0.797
Ratio of owners equity to gross assets IFRS (5-year summary)CurrentYearInstant0.806
Rate of return on equity IFRS (5-year summary)Prior4YearDuration0.073
Rate of return on equity IFRS (5-year summary)Prior3YearDuration0.071
Rate of return on equity IFRS (5-year summary)Prior2YearDuration0.102
Rate of return on equity IFRS (5-year summary)Prior1YearDuration0.071
Rate of return on equity IFRS (5-year summary)CurrentYearDuration0.077
Price earnings ratio IFRS (5-year summary)Prior4YearDuration32.2
Price earnings ratio IFRS (5-year summary)Prior3YearDuration29.4
Price earnings ratio IFRS (5-year summary)Prior2YearDuration15.7
Price earnings ratio IFRS (5-year summary)Prior1YearDuration21.0
Price earnings ratio IFRS (5-year summary)CurrentYearDuration19.7
Cash flows from used in operating activities IFRS (5-year summary)Prior4YearDuration86548000000JPY
Cash flows from used in operating activities IFRS (5-year summary)Prior3YearDuration48672000000JPY
Cash flows from used in operating activities IFRS (5-year summary)Prior2YearDuration115551000000JPY
Cash flows from used in operating activities IFRS (5-year summary)Prior1YearDuration67884000000JPY
Cash flows from used in operating activities IFRS (5-year summary)CurrentYearDuration96619000000JPY
Cash flows from used in investing activities IFRS (5-year summary)Prior4YearDuration-11363000000JPY
Cash flows from used in investing activities IFRS (5-year summary)Prior3YearDuration-17185000000JPY
Cash flows from used in investing activities IFRS (5-year summary)Prior2YearDuration-20382000000JPY
Cash flows from used in investing activities IFRS (5-year summary)Prior1YearDuration-142387000000JPY
Cash flows from used in investing activities IFRS (5-year summary)CurrentYearDuration-89189000000JPY
Cash flows from used in financing activities IFRS (5-year summary)Prior4YearDuration-28446000000JPY

Every row of the EDINET CSV. Item names are the XBRL element names; filed text is kept in its original Japanese. Filed text is available on Plus and Pro.

Data checks · 21 of 21 passed
balance sheet identityconsolidated 2024-12-31pass rounding
balance sheet identityconsolidated 2025-12-31pass
balance sheet identitynon_consolidated 2024-12-31pass
balance sheet identitynon_consolidated 2025-12-31pass
dei present pass
period resolution pass
statement vs summary · net assetsnon_consolidated 2023-12-31pass
statement vs summary · net assetsnon_consolidated 2024-12-31pass
statement vs summary · net assetsnon_consolidated 2025-12-31pass
statement vs summary · net income attributable to parentconsolidated 2024-01-01/2024-12-31pass
statement vs summary · net income attributable to parentconsolidated 2025-01-01/2025-12-31pass
statement vs summary · operating cash flowconsolidated 2024-01-01/2024-12-31pass
statement vs summary · operating cash flowconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenueconsolidated 2024-01-01/2024-12-31pass
statement vs summary · revenueconsolidated 2025-01-01/2025-12-31pass
statement vs summary · revenuenon_consolidated 2024-01-01/2024-12-31pass
statement vs summary · revenuenon_consolidated 2025-01-01/2025-12-31pass
statement vs summary · total assetsconsolidated 2024-12-31pass
statement vs summary · total assetsconsolidated 2025-12-31pass
statement vs summary · total assetsnon_consolidated 2024-12-31pass
statement vs summary · total assetsnon_consolidated 2025-12-31pass